The Physiological Effect of RCexp on Ventilation/Perfusion Distribution
The Physiological Effect of RCexp on Ventilation/Perfusion Distribution in Patients With ARDS
Southeast University, China
60 participants
Nov 30, 2025
OBSERVATIONAL
Conditions
Summary
With the exception of setting the positive end-expiratory pressure (PEEP), the expiratory phase is commonly overlooked during MV. The expiratory time constant (RCexp) plays an important role in understanding the mechanical properties of the respiratory system in patients receiving mechanical ventilation. However, it is unclear that the effect of expiratory time constant on the ventilation and perfusion distribution.
Eligibility
Inclusion Criteria1
- adult patients with ARDS receiving mechanical ventilation no more than 72 hours
Exclusion Criteria6
- age <18 years old
- patient undergoing legal protection
- contra-indications to EIT (e. g. severe chest trauma or wounds)
- pneumothorax
- patient undergoing ECMO
- pregnancy
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Interventions
patients received different RCexp
Locations(1)
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NCT06919484