Mechanical Ventilation Clinical Trials

67 recruiting

Mechanical Ventilation Trials at a Glance

128 actively recruiting trials for mechanical ventilation are listed on ClinicalTrialsFinder across 6 cities in 35 countries. The largest study group is Not Applicable with 67 trials, with the heaviest enrollment activity in Paris, Beijing, and Nanjing. Lead sponsors running mechanical ventilation studies include Assistance Publique - Hôpitaux de Paris, University Health Network, Toronto, and Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA).

Browse mechanical ventilation trials by phase

Treatments under study

About Mechanical Ventilation Clinical Trials

Looking for clinical trials for Mechanical Ventilation? There are currently 67 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Mechanical Ventilation trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Mechanical Ventilation clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 128 trials

Recruiting

Intelligent Lung Support in the Intensive Care Unit

Intensive Care MedicineMechanical Ventilation
Technische Universität Dresden530 enrolled5 locationsNCT06595602
Recruiting

Effects of AbClo Fascial Approximation Device in Patients With Open Abdomen on Respiratory Mechanics

Mechanical VentilationOpen Abdomen
Unity Health Toronto18 enrolled1 locationNCT07154589
Recruiting
Phase 2

Fentanyl Versus Hydromorphone in Patients on Mechanical Ventilation

Mechanical VentilationSedation and AnalgesiaCritical Care, Intensive Care
Beth Israel Deaconess Medical Center300 enrolled1 locationNCT07224620
Recruiting

Predictive Algorithms for Critical Rehabilitation Outcomes

Mechanical VentilationRehabilitationIntensive Care+1 more
Wuhan University250 enrolled1 locationNCT06532994
Recruiting
Not Applicable

Sedation in ICU Patients With Mechanical Ventilation

Mechanical VentilationSedation
Zhongda Hospital366 enrolled1 locationNCT06538883
Recruiting
Not Applicable

Hydrogen Peroxide and Ultraviolet Light for Disinfecting Surfaces in Intensive Care Units

Infection, HospitalAntimicrobialPneumonia Associated With Mechanical Ventilation
Hospital Israelita Albert Einstein5,000 enrolled12 locationsNCT07233837
Recruiting
Not Applicable

Effect of Post-suction Recruitment on Lung Volume in Mechanically Ventilated ICU Patients

Mechanical Ventilation
Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer32 enrolled1 locationNCT07358039
Recruiting

Multidimensional Correlation Analysis of Heart Rate Variability and Weaning Assessment Parameters in Critically Mechanically Ventilated Patients

Weaning Invasive Mechanical Ventilation
Fu Jen Catholic University Hospital100 enrolled1 locationNCT07455214
Recruiting
Phase 1Phase 2

Influence of Personalized Lung Volume Optimization Maneuver on Lung Function and Cardiac Performance in Children

Mechanical VentilationCongenital Heart DiseaseChildren+8 more
Charite University, Berlin, Germany80 enrolled1 locationNCT07193719
Recruiting
Not Applicable

Effects of Periodic Recruitment Maneuvers on Atelectasis and Respiratory Mechanics During Elective Spine Surgery Assessed by Lung Ultrasonography

AtelectasisGeneral AnesthesiaMechanical Ventilation+1 more
Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization60 enrolled1 locationNCT07325812
Recruiting

Retrospective Study on Ventilator Weaning Outcomes in Patients With Acute Brain Injury

Mechanical VentilationAcute Brain Injuries
Southeast University, China1,500 enrolled1 locationNCT07496125
Recruiting

Use of a Physiotherapy Assessment to Predict Extubation Failure in Mechanically Ventilated Patients: the EPIC Assessment

Mechanical VentilationMechanical Ventilator Weaning
Assistance Publique - Hôpitaux de Paris330 enrolled1 locationNCT06450678
Recruiting
Not Applicable

Neuromuscular Electrical Stimulation in a Patient on Invasive Mechanical Ventilation (MOVCARE)

Mechanical VentilationCritical IllnessNeuromuscular Electrical Stimulation (NMES)+2 more
Hospital Moinhos de Vento150 enrolled1 locationNCT07188350
Recruiting

Prediction of Extubation Failure: A Multicenter Prospective Observational Study

Mechanical Ventilation
Chongqing Medical University2,604 enrolled1 locationNCT05069441
Recruiting
Not Applicable

Turkish Validity and Reliability of the Behavioral Indicators of Pain Scale(ESCID)

Mechanical Ventilation
Saglik Bilimleri Universitesi50 enrolled1 locationNCT07467551
Recruiting
Not Applicable

The ED-AWARENESS-2 Trial

Mechanical VentilationPTSDAwareness+1 more
Washington University School of Medicine3,090 enrolled4 locationsNCT05534243
Recruiting
Not Applicable

Flow-Controlled Versus Volume-Controlled Ventilation in Bariatric Surgery

ObesityBariatric SurgeryMechanical Ventilation
Ankara Etlik City Hospital40 enrolled1 locationNCT07430111
Recruiting
Not Applicable

Impact of PEEP on Respiratory Effort During Assisted Ventilation

Respiratory FailureMechanical VentilationEffort
Pontificia Universidad Catolica de Chile12 enrolled1 locationNCT07437846
Recruiting
Not Applicable

Platform of Randomized Adaptive Clinical Trials in Critical Illness

Respiratory InsufficiencyMechanical Ventilation Pressure HighExtracorporeal Membrane Oxygenation Complication
University Health Network, Toronto6,250 enrolled86 locationsNCT05440851
Recruiting
Phase 3

Optimizing Pain Treatment in Children On Mechanical Ventilation

Mechanical VentilationSedation and AnalgesiaAnalgesics, Opioid+1 more
Weill Medical College of Cornell University644 enrolled15 locationsNCT06994442