RecruitingNCT06921733

Ultrasound Localization Microscopy in Patient With Congenital Anomalies of the Kidney and Urinary Tract (CAKUT)

Non-invasive Evaluation of Kidneys in Patient With Congenital Anomalies of the Kidney and Urinary Tract (CAKUT) Using Ultrasound Localization Microscopy


Sponsor

University of Erlangen-Nürnberg Medical School

Enrollment

20 participants

Start Date

May 13, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

This clinical study aims to non-invasively visualize perfusion and microvascularization, as well as individual glomeruli, using Ultrasound Localization Microscopy (ULM) and CEUS in patients with congenital anomalies of the kidney and urinary tract (CAKUT).


Eligibility

Min Age: 0 MonthsMax Age: 6 Years

Inclusion Criteria1

  • Minimum Age 1 Month Maximum Age 6 Years Indication for MAG3 Scintigraphy of the Kidney Congenital Anomalies of the Kidney and Urinary Tract Obstruction Diagnosis Availability of the qualified examiner Consent of the parents/legal guardians

Exclusion Criteria1

  • Lack of consent of at least one parent

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Interventions

DEVICEContrast enhanced ultrasound imaging (CEUS) and post processing with ULM

CEUS is a contrast based ultrasound technique and ULM (Ultrasound Localization Microscopy) is a post-processing bioinformatical method to quantify microvascular architecture and perfusion dynamics.


Locations(1)

FAU Erlangen-Nuernberg,

Erlangen, Bavaria, Germany

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NCT06921733


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