Pacemaker-related Tricuspid Regurgitation Progression and Long-term Outcomes
Predictors of Tricuspid Regurgitation Progression and Adverse Outcomes in Different Pacing Modes
Haiyan Wang
200 participants
Apr 1, 2025
OBSERVATIONAL
Conditions
Summary
Tricuspid regurgitation (TR) is a common complication following cardiac implantable electronic device (CIED) implantation, with severe TR being associated with increased rates of heart failure hospitalization and all-cause mortality, significantly impairing patients' quality of life. With technological advancements, physiological pacing modalities have demonstrated superior clinical efficacy and safety profiles compared to conventional pacing methods. This study aims to evaluate predictors of adverse outcomes and TR progression in CIED recipients under different pacing modalities, thereby providing clinical guidance for high-risk patients.
Eligibility
Inclusion Criteria3
- Adult patients
- Patients with an implantable electronic heart device (CIEDs)
- The patient underwent pacemaker implantation at Qianfoshan Hospital between 2015 and 2025
Exclusion Criteria3
- Patients with severe tricuspid regurgitation or those who have undergone tricuspid valve surgery or interventional treatment prior to pacemaker implantation
- Patients with severe valvular heart disease, congenital heart disease, or arrhythmias
- Patients with single-chamber pacemakers or poor images
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Interventions
Pacemaker implantation methods include right ventricular pacing, biventricular pacing, conduction system pacing
Locations(1)
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NCT06922526