RecruitingNot ApplicableNCT06923397

Interrupting Sedentary Time to Improve Cardiometabolic Health and Toxicity in Patients With Lymphoma Receiving Chemotherapy: The iSTAND Trial

Sponsor

Dana-Farber Cancer Institute

Enrollment

24 participants

Start Date

Jun 5, 2025

Study Type

INTERVENTIONAL

Conditions

Lymphoma Sedentary Behavior Lymphoma, Non-Hodgkin Lymphoma, Hodgkin

Summary

This study aims to see if a 12-week exercise program designed to reduce long periods of inactivity is feasible in newly diagnosed lymphoma participants receiving R-CHOP or POLA-R-CHP chemotherapy treatments, and whether it can improve heart health and reduce chemotherapy drug side effects.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether breaking up prolonged sitting time during chemotherapy can help lymphoma patients maintain heart health and reduce treatment side effects. Participants will receive reminders to move and stand more throughout the day while undergoing standard chemotherapy. **You may be eligible if...** - You have been diagnosed with lymphoma - You are starting first-line R-CHOP or POLA-R-CHP chemotherapy - You are 18 or older - You currently exercise less than 60 minutes per week of moderate-to-vigorous activity - You have a doctor's clearance to exercise - You speak English and can travel to Dana-Farber Cancer Institute - You have a phone that can receive text messages **You may NOT be eligible if...** - You have unstable medical conditions that prevent physical activity - You do not have access to or cannot travel to Dana-Farber for sessions - You are under 18 Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALInterrupted Sedentary Time Intervention

A 12-week, semi-supervised exercise intervention comprised of reminder prompts, counseling, and activities of walking, cycling, and resistance band exercise for at-home and in-clinic settings. Supervision will be under an exercise trainer. Resistance bands, Libre Pro continuous blood sugar monitor, and Fitbit and ActivPAL trackers will be provided to participants.