RecruitingNot ApplicableNCT06923618

Cancer of the Lung And SeneScencE - Prospective Cohort 1

Identification of Aging Biomarkers for Better Tailoring of Cancer Treatment in Older Patients With Lung Cancer: a Multicenter Clinico-biological Cohort Study


Sponsor

Assistance Publique - Hôpitaux de Paris

Enrollment

385 participants

Start Date

Jul 9, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The main objective is to identify and assess the predictive value of ageing and senescence biomarkers (methylome, telomeres, inflammageing) and senescent cells in tissues to improve prognosis assessment older patients with locally or locally-advanced Non-Small Cell Lung Cancer (NSCLC).


Eligibility

Min Age: 70 Years

Plain Language Summary

Simplified for easier understanding

This study is following older patients with non-small cell lung cancer (a common type of lung cancer) to understand how aging-related changes in the body affect their recovery from surgery. The goal is to improve surgical planning and outcomes for elderly patients. **You may be eligible if...** - You are 70 years or older - You have early to locally advanced lung cancer (stage I–IIIA) that may be lung cancer based on scans or confirmed by biopsy - You are being considered for surgery to remove the cancer - You are enrolled in the French social security system **You may NOT be eligible if...** - You have been diagnosed with another active cancer (other than certain treated skin or prostate cancers) in the last 6 months - You are legally under guardianship or not able to give informed consent - You cannot understand or agree to the study requirements Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

BIOLOGICALBlood samples

Blood samples (5 ml) during surgery or within 3 days before.


Locations(1)

Henri Mondor Hospital

Créteil, Île-de-France Region, France

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT06923618


Related Trials