RecruitingNot ApplicableNCT06929650

The Safety and Feasibility of Radiofrequency Ablation to Treat Low-risk Thyroid Cancer

Thermo-Ablation With Radiofrequency Medical Technologies to Treat Thyroid Cancers

Sponsor

University Health Network, Toronto

Enrollment

40 participants

Start Date

Apr 20, 2023

Study Type

INTERVENTIONAL

Conditions

Thyroid Cancer Thyroid Nodule

Summary

The goal of this clinical trial is to test radiofrequency ablation (RFA) in thyroid cancers ≤2 cm in diameter. The main question it aims to answer is: • What is the feasibility of RFA use for low-risk thyroid cancers (≤2 cm)? Participants will undergo a set of pre-procedural scans of the target thyroid nodule and undergo the RFA procedure/intervention. Then, participants will partake in three follow-up appointments at 4 weeks, 6 months, and 12 months post-procedure as per standard of care.

Eligibility

Min Age: 18 YearsMax Age: 100 Years

Inclusion Criteria6

\. Patients with:
Nodule less than or equal to 2cm in size
a. Specifically: Bethesda 5/6
Their age is ≥18 years and ≤100 years
Able to provide written consent
Able to attend required follow-ups as per the protocol

Exclusion Criteria4

Patients \<18 years old
Pregnant women
Any concern for invasive or metastatic thyroid cancer
Previously treated for thyroid cancer

Interventions

PROCEDURERadiofrequency ablation

Radiofrequency energy is delivered to the thyroid nodule via the medical device. This device is a system consisting of 3 main components: 1. VIVA combo RF system (generator and pump) 2. single foot switch 3. electrode (5mm, 7mm, 10mm, or adjustable).