RecruitingNot ApplicableNCT06929650

The Safety and Feasibility of Radiofrequency Ablation to Treat Low-risk Thyroid Cancer

Thermo-Ablation With Radiofrequency Medical Technologies to Treat Thyroid Cancers

Sponsor

University Health Network, Toronto

Enrollment

40 participants

Start Date

Apr 20, 2023

Study Type

INTERVENTIONAL

Conditions

Thyroid Cancer Thyroid Nodule

Summary

The goal of this clinical trial is to test radiofrequency ablation (RFA) in thyroid cancers ≤2 cm in diameter. The main question it aims to answer is: • What is the feasibility of RFA use for low-risk thyroid cancers (≤2 cm)? Participants will undergo a set of pre-procedural scans of the target thyroid nodule and undergo the RFA procedure/intervention. Then, participants will partake in three follow-up appointments at 4 weeks, 6 months, and 12 months post-procedure as per standard of care.

Eligibility

Min Age: 18 YearsMax Age: 100 Years

Plain Language Summary

Simplified for easier understanding

This study tests whether radiofrequency ablation — a minimally invasive procedure that uses heat to destroy tissue — is safe and effective for treating small, low-risk thyroid nodules that appear to be cancerous, as an alternative to surgery. **You may be eligible if...** - You are 18 years or older - You have a thyroid nodule that is 2 cm or smaller in size - Your nodule has been classified as suspicious or likely cancerous (Bethesda category 5 or 6) - You are able to attend required follow-up visits **You may NOT be eligible if...** - You are under 18 years old - You are pregnant - There is concern that the cancer has spread or invaded nearby structures - You have previously been treated for thyroid cancer Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

PROCEDURERadiofrequency ablation

Radiofrequency energy is delivered to the thyroid nodule via the medical device. This device is a system consisting of 3 main components: 1. VIVA combo RF system (generator and pump) 2. single foot switch 3. electrode (5mm, 7mm, 10mm, or adjustable).