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RecruitingNot ApplicableNCT06930183

Awake Thoracic Epidural Anesthesia Versus General Anesthesia in Thoracotomy

Awake Thoracic Epidural Anesthesia Versus General Anesthesia in Thoracotomy: A Randomized Controlled Trial

Sponsor

Cairo University

Enrollment

50 participants

Start Date

Apr 16, 2025

Study Type

INTERVENTIONAL

Conditions

AwakeThoracic Epidural AnesthesiaGeneral AnesthesiaThoracotomy

Summary

This study aims to compare awake thoracic epidural anesthesia and general anesthesia in thoracotomy.

Eligibility

Min Age: 18 YearsMax Age: 75 Years

Inclusion Criteria4

  • Age from 18 to 75 years old.
  • Both genders.
  • American Society of Anesthesiologists (ASA) physical status classification II or III.
  • Scheduled for thoracotomy.

Exclusion Criteria6

  • Difficult airway management,
  • Hemodynamically unstable patients, obesity (body mass index \>30).
  • Absolute contraindication to thoracic epidural anesthesia such as (patient refusal, allergy to local anesthetics, coagulopathy, active neurologic disorders, skin infection at insertion site, uncooperative patients, uncontrolled cough, and unfavorable anatomy for thoracic epidural).
  • Neurological disorders: risk of seizure, unable to cooperate, intracranial mass or brain edema, extensive pleural adhesions or previous pulmonary resections, hypoxemia (PaO2 \<60) or hypercarbia (PaCO2 \>50)
  • Poor cardiac function (ejection fraction less than 50%).
  • Patients with bad pulmonary function tests.
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Interventions

DRUGAwake thoracic epidural anesthesia

Patients will preoperatively receive awake thoracic epidural anesthesia.

DRUGGeneral anesthesia

Patients will receive general anesthesia.

Locations(1)

Cairo University

Cairo, Egypt

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NCT06930183

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