Types of Intracellular Bacteria in Atherosclerotic Plaques and Analysis of Risk Factors

This study is investigating what types of bacteria live inside the walls of arteries affected by atherosclerosis (plaque buildup that leads to heart attacks and strokes). Researchers suspect certain bacteria may contribute to inflammation inside artery walls, and understanding this connection could lead to new prevention or treatment strategies. **You may be eligible if...** - You are undergoing surgery to remove atherosclerotic plaque from your arteries (such as carotid endarterectomy) - You are an adult with confirmed atherosclerotic disease - You consent to having a small tissue sample from the plaque examined **You may NOT be eligible if...** - You have recently used antibiotics (which could alter bacteria in the plaque) - You have active infections or immune system disorders - You are not undergoing plaque removal surgery at a participating center Talk to your doctor to see if this trial is right for you.