Comparison of the Effects of Bimanual, Finger and VR Exercises in PwMCI
Comparison of the Effects of Bimanual, Finger and Virtual Reality Exercises in Individuals With Mild Cognitive Impairment - Randomized Controlled Study
Eastern Mediterranean University
106 participants
Apr 29, 2025
INTERVENTIONAL
Conditions
Summary
Mild Cognitive Impairment (MCI) is defined as an impairment in a single cognitive function, usually memory, other than normal cognitive decline with age, that does not fulfil dementia criteria. Finger movements have been shown to stimulate the sensory-motor and cognitive parts of the cerebral cortex, as well as the supplementary motor area, Broca's area, premotor cortex, and prefrontal cortex, all of which contribute to movement skills. Asymmetrical hand and finger movements done concurrently were proven to improve cognitive processes and cerebral blood flow more than movements performed with one hand.
Eligibility
Inclusion Criteria7
- Participants who are between 50-75 years of age
- Individuals diagnosed with MCI by a geriatrician according to DSM-5 criteria,
- Who has the Montreal Cognitive Assessment score between 13-26,
- Who has the Quick Mild Cognitive Impairment screen score between 48-67,
- Who has Instrumental Activities of Daily Living Scale score ≥6/8,
- Who says yes to "Do you have a memory problem?" question,
- Who can walk independently without using any walking aids
Exclusion Criteria5
- Participants who have any musculoskeletal disorders that may cause balance and gait disorders,
- Who have central or peripheral neurological diseases (eg. stroke, Parkinson's disease or polyneuropathies),
- Who are using psychiatric drugs that may affect psychiatric disease and/or cognitive performance (Using nonsteroidal anti-inflammatory drugs more than three times a week, which may affect cognitive functions, using gingko biloba and antioxidant supplements (for example, coenzyme Q10 and alpha-lipoic acid)),
- Who has daltonism and
- Who attends any exercise program last 6 months will not be included in this study.
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Interventions
The bimanual exercise group consists of exercises that involve movements in which both hands are used simultaneously. The bimanual exercise group will have 40 minutes of training for 3 sessions per week for 8 weeks.
The finger exercise group consists of exercises that involve finger movements. The bimanual exercise group will have 40 minutes of training for 3 sessions per week for 8 weeks.
The virtual reality exercise group consists of hand-tracking game exercises that involve finger movements. The bimanual exercise group will have 40 minutes of training for 3 sessions per week for 8 weeks.
Locations(1)
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NCT06935812