Endoscopic Therapy Or Surgery for Early Colon Cancer

This trial is comparing two treatments for small early-stage colon cancer: endoscopic removal (using a scope without surgery) versus surgical removal, to find out whether the less invasive approach is as effective. **You may be eligible if...** - You have newly diagnosed colon cancer (adenocarcinoma) that is 20 mm or smaller and suspected to have grown into the lining but not deeply - There are no high-risk features on biopsy (no high-grade cancer, lymph vessel invasion, or significant budding) - The cancer has not spread beyond the colon wall (no involvement of lymph nodes or distant sites) - You are eligible for surgery if needed - You have no prior colorectal cancer and no more than 10 polyps **You may NOT be eligible if...** - Your cancer shows high-risk features or is larger than 20 mm - There is evidence of spread beyond the colon - You have a genetic cancer syndrome (like Lynch syndrome or polyposis) - You have another active cancer Talk to your doctor to see if this trial is right for you.