RecruitingNot ApplicableNCT06941155

Gamified Combined Cognitive Bias Modification in Adults Diagnosed With OCD: Randomized Controlled Trial

A Randomized Controlled Trial on the Effects of Mobile-Based Gamified Combined Cognitive Bias Modification on OCD Symptoms, Obsessive Beliefs, Cognitive Biases, Depressive Symptoms and Distress in Adults Diagnosed With OCD


Sponsor

Dokuz Eylul University

Enrollment

90 participants

Start Date

May 14, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This randomized controlled trial examines the effects of a mobile-based gamified combined cognitive bias modification (CBM-C) intervention on obsessive-compulsive symptoms, obsessive beliefs, attentional and interpretation biases, depressive symptoms, and psychological distress. The gamified CBM-C condition is compared to a standard mobile-based CBM-C and a placebo control condition. All interventions are delivered via a mobile application. Assessments are conducted at baseline, post-intervention (week 4), and 3-month follow-up.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This trial is testing a gamified (game-like) online mental training program for adults with OCD to help reduce their obsessive thoughts and anxiety by changing how the brain automatically reacts to certain triggers. **You may be eligible if...** - You are 18 or older - You have been diagnosed with OCD by a licensed mental health professional - You have had stable psychiatric medication (no dose changes) for at least one month - You have access to the internet and a smartphone - You are not currently in another intervention study or receiving other psychological therapy - You have no active suicidal thoughts or psychotic symptoms **You may NOT be eligible if...** - You have active suicidal ideation or psychosis - Your psychiatric medication has changed recently or is expected to change during the study - You have a significant neurological condition that could interfere with the program - You have color blindness Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALGamified-Combined Cognitive Bias Modification

A gamified version of the combined cognitive bias modification (CBM-C) intervention, which includes both attention and interpretation bias modification tasks. The attention component is a modified dot-probe task, and the interpretation component consists of OCD-related scenarios with word-completion exercises. Gamification elements such as feedback and visual rewards are embedded to enhance motivation and engagement. The presentation order of the two intervention components will be counterbalanced: half of the participants will receive the attention bias task first followed by the interpretation task; the other half will receive the interpretation task first followed by the attention bias task. The intervention is delivered via mobile phone in eight sessions over four weeks (two sessions per week).

BEHAVIORALStandard Combined Cognitive Bias Modification

A standard version of the combined cognitive bias modification (CBM-C) intervention, consisting of attention and interpretation bias tasks without gamification features. The attention task is a modified dot-probe paradigm, and the interpretation task involves OCD-related scenarios followed by word-completion exercises. The presentation order of the two intervention components will be counterbalanced: half of the participants will receive the attention bias task first followed by the interpretation task; the other half will receive the interpretation task first followed by the attention bias task. The intervention is delivered via mobile phone in eight sessions over four weeks (two sessions per week).

BEHAVIORALPlacebo

A placebo version of the standard CBM-C intervention that retains the same structure and timing but omits all active bias modification elements. The attention task (modified dot-probe) presents probes equally behind threat and neutral stimuli, and the interpretation task includes OCD-related scenarios with word-completion items that lead to neutral outcomes. No manipulations are applied to shift cognitive bias. The presentation order of the two intervention components will be counterbalanced: half of the participants will receive the attention bias task first followed by the interpretation task; the other half will receive the interpretation task first followed by the attention bias task. The intervention is delivered via mobile phone in eight sessions over four weeks (two sessions per week).


Locations(1)

Dokuz Eylul University Hospital

Izmir, Turkey (Türkiye)

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NCT06941155


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