RecruitingNot ApplicableNCT07206212

A Lifestyle Intervention to Reduce Cardiometabolic Risk Factors in Individuals With Obsessive-compulsive Disorder

Efficacy and Cost-effectiveness of a Lifestyle Intervention to Reduce Cardiometabolic Risk Factors in Individuals With Obsessive-compulsive Disorder: A Randomized Controlled Trial


Sponsor

Karolinska Institutet

Enrollment

108 participants

Start Date

Jan 30, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The overall aim of this study is to evaluate the efficacy and cost-effectiveness of a lifestyle intervention to improve lifestyle habits and reduce cardiometabolic risk factors in individuals with obsessive-compulsive disorder (OCD).


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing a lifestyle intervention — focused on increasing physical activity — to help reduce cardiovascular and metabolic risk factors (like high blood pressure, blood sugar, and cholesterol) in people with obsessive-compulsive disorder (OCD). People with OCD often have higher rates of these physical health problems, partly due to sedentary lifestyles. **You may be eligible if...** - You have a confirmed diagnosis of OCD (based on a formal psychiatric interview) - You are 18 or older - You are currently not meeting national physical activity guidelines — meaning less than 150 minutes of moderate activity per week during the past month **You may NOT be eligible if...** - You have an intellectual disability or severe psychiatric symptoms that would interfere with the program - You have a high risk of suicide at this time - You have an eating disorder or substance use disorder - You have serious physical conditions that prevent exercise - You are pregnant Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALA group-based lifestyle intervention for individuals with OCD

Participants will take part in 13 week program, with one individual session to set up goals for a change of lifestyle habits, based on the baseline evaluation of their clinical characteristics, lifestyle habits, and cardiometabolic risk, and 12 group sessions, consisting of both education on lifestyle habits and physical exercise. Each educational session will focus on a specific topic/lifestyle habit, alternating more informative sessions with sessions discussing how the information can be applied, taking into account specific hinders due to Obsessive-Compulsive Disorder. Between-sessions homework will include, for example, daily registration of physical activity and implementing changes in the lifestyle habits discussed during each session. All homework assignments will be registered in a digital platform. After the 13 weeks of lifestyle intervention, participants will get access to a booster module in the digital platform to help them maintain their behavioral changes.

BEHAVIORALMedical and lifestyle advice

One individual session with a clinical psychologist on week 1 of about 1 hour of duration. During this session, participants will receive feedback based on the baseline evaluation of their clinical characteristics, lifestyle habits, and cardiometabolic risk. Participants also receive written educational information on healthy lifestyle habits based on national Swedish guidelines issued by the National Board of Health and Welfare. The recommendations include engaging in regular physical activity, dietary guidelines based on Nordic Nutrition Recommendations, and advice to reduce alcohol consumption and quit tobacco use.


Locations(1)

OCD-Programmet, Psykiatri Sydväst

Huddinge, Stockholm County, Sweden

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NCT07206212


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