RecruitingPhase 3NCT06941441

PAH Exercise Study

Remotely-Monitored Exercise to Enhance Functional Outcomes in Patients With Pulmonary Arterial Hypertension (PAH) Initiating Sotatercept Therapy: A Single-site Feasibility Study

Sponsor

University of Washington

Enrollment

10 participants

Start Date

Apr 15, 2025

Study Type

INTERVENTIONAL

Conditions

Exercise Therapy Pulmonary Arterial Hypertension PAH

Summary

Ten patients with PAH who are stable and eligible to initiate sotatercept therapy will participate in a 26 week study that consists of a 24-week intervention period where patients will receive complimentary sotatercept as prescribed, plus a tailored, progressive home exercise program with wrist-worn fitness tracker and oxygen saturation monitoring.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is exploring how a structured home exercise program affects patients with pulmonary arterial hypertension (PAH — a type of high blood pressure in the lungs) who are about to start a newer medication called sotatercept. **You may be eligible if...** - You are 18 or older - You have been diagnosed with Group 1 PAH (confirmed by a right heart catheterization procedure) - Your symptoms are classified as WHO Functional Class II or III (moderate limitation during activity) - You have been on stable PAH medication for at least 90 days - Your doctor has recommended starting sotatercept - You are willing and able to participate in a home exercise program for 24 weeks **You may NOT be eligible if...** - You have been recently hospitalized for a heart or lung issue - You have severe exercise limitations or unstable conditions - You are already on sotatercept - You are pregnant or planning to become pregnant Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

OTHERHome exercise program

A tailored, progressive home exercise program with wrist-worn fitness tracker and oxygen saturation monitoring

Locations(1)

University of Washington

Seattle, Washington, United States

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT06941441

Related Trials

Early Exercise-Based Rehabilitation in Patients Hospitalized for Acute Pulmonary Embolism

NCT071435396 locations

Study of Intravenous ZMA001 in Healthy Subjects

NCT059672991 location

A Study of ROC-101 in Patients With Pulmonary Arterial Hypertension (PAH) and Pulmonary Hypertension Associated With Interstitial Lung Disease (ILD-PH) (ROCSTAR STUDY)

NCT0717503819 locations

Study of REGN13335 in Adult Participants With Pulmonary Arterial Hypertension (PAH)

NCT073185976 locations

A Phase Ⅰb/Ⅱa Clinical Study of IMC-003 Injection for the Treatment of Pulmonary Arterial Hypertension Receiving Background Therapy.

NCT0759302732 locations