RecruitingNCT06943807

Prospective Gastric Cancer Screening With Fecal Multi-target DNA Analysis

A Prospective Study of Gastric Cancer Screening Based on Fecal Multi-Target DNA Analysis Combined With a Risk Questionnaire

Sponsor

Fudan University

Enrollment

15,000 participants

Start Date

Jul 1, 2025

Study Type

OBSERVATIONAL

Conditions

Gastric (Stomach) Cancer

Summary

This is a prospective study designed to evaluate the efficacy of a multi-target fecal DNA test for the early detection of gastric cancer. The test combines Helicobacter pylori gene detection with analysis of fecal methylated DNA markers. The primary objective is to assess whether each method, individually or in combination, can facilitate earlier diagnosis of gastric cancer. All participants will undergo the multi-target fecal DNA test and complete the gastric cancer risk questionnaire.

Eligibility

Min Age: 40 Years

Plain Language Summary

Simplified for easier understanding

This study is testing a new non-invasive screening approach — analysing a stool (faecal) sample for multiple DNA markers — to detect early signs of gastric (stomach) cancer or precancerous changes, potentially as an alternative to endoscopy. **You may be eligible if...** - You are 40 years of age or older - You have no contraindications to an endoscopy procedure - You are able to give informed consent in person **You may NOT be eligible if...** - You have a previous history of stomach cancer or other digestive tract cancers - You have severe underlying heart, lung, liver, or kidney disease - You have a severe mental illness preventing participation - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

People's Hospital of Tongling City

Tongling, China

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NCT06943807

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