A Study of BBT002 in Healthy Volunteers (HVs) and in Adult Patients With Chronic Obstructive Pulmonary Disease (COPD) or Chronic Rhiosininusitis With Nasal Polyps (CRSwNP)

This study is testing a new inhaled medication called BBT002 in healthy volunteers and in people with chronic obstructive pulmonary disease (COPD), a lung condition that makes it hard to breathe. The goal is to assess how safe and effective it is. **You may be eligible if...** - You are between 18–65 years old (healthy volunteers) or 35–75 years old (COPD patients) - Your body weight and BMI fall within the study's acceptable range - You are a non-smoker, light smoker (5 or fewer cigarettes per day), or ex-smoker - For the COPD part: you have a documented COPD diagnosis and your lung function meets the study criteria - You are using adequate contraception if applicable **You may NOT be eligible if...** - You have significant heart, liver, kidney, or other organ problems - You are pregnant or breastfeeding - You have recently used other medications that could interfere with the study drug - Your COPD is currently very poorly controlled or you've had a recent flare-up Talk to your doctor to see if this trial is right for you.