RecruitingPhase 3NCT06947330

Comparison Between Erector Spinae Plane Block Versus Serratus Anterior Plane Block Regarding Analgesia Post Modified Radical Mastectomy

Comparison Between Ultrasound Guided Erector Spinae Plane Block Versus Ultrasound Guided Serratus Anterior Plane Block Regarding Analgesia Post Modified Radical Mastectomy


Sponsor

Kholoud Usama

Enrollment

100 participants

Start Date

Mar 3, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical trial is to compare Ultrasound Guided Erector Spinae and Ultrasound Guided Serratus Anterior Plane Block post Modified Radical Mastectomy in adult females. the main questions it aims to answer are: * Which of the two blocks has a better analgesic effect? * Which of the two blocks is safer as regards inducing a pneumothorax and affecting the hemodynamics? Participants: * Will be divided into two groups after signing the informed consent. * After being anesthetized and before surgical incision; the blocks will be given to the patient. * Lung Ultrasound will be done for each patient to rule out pnemothorax once before the surgery and another after the end of surgery while the patient is being anesthetized. * Patients that will experience pneuomothorax will be excluded from the study, and will be treated according to its size. * Follow up of the patient for 24 hours postoperative to record the VAS score continuously, with giving increments of pethidine intravenously to relief pain.


Eligibility

Sex: FEMALEMin Age: 21 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This study is comparing two types of nerve blocks (regional anaesthesia techniques) for pain control after a modified radical mastectomy (removal of the breast and surrounding lymph nodes): the erector spinae plane block versus the serratus anterior plane block. **You may be eligible if...** - You are a woman between 21 and 65 years old - You are classified as moderate-to-high surgical risk (ASA class II or III) - You are scheduled for a modified radical mastectomy **You may NOT be eligible if...** - You are classified as ASA IV, V, or VI (highest-risk patients) - You have an infection at the injection site for the nerve block - You have a bleeding disorder or are taking blood thinners (anticoagulants or antiplatelets) - You have a known allergy to bupivacaine (the local anaesthetic used) - Your cancer has spread to distant organs (metastatic) - You are male Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREUnilateral Erector Spinae group

On injecting 30 ml of bupivacaine 0.25% with 20 mcg Dexamedetomidine into the interfacial plane below erector spinae; a manifest linear pattern will be visualized uplifting the muscle.

PROCEDUREUnilateral Serratus Anterior group

Once the needle will be in perfect position, confirmed by hydro-dissection on injecting 2-3 ml of normal saline, then 30 ml of bupivacaine 0.25% with 20 mcg Dexamedetomidine.


Locations(1)

Faculty of Medicine, Ain-Shams University

Cairo, Waili, Egypt

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NCT06947330


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