RecruitingPhase 3NCT06947330

Comparison Between Erector Spinae Plane Block Versus Serratus Anterior Plane Block Regarding Analgesia Post Modified Radical Mastectomy

Comparison Between Ultrasound Guided Erector Spinae Plane Block Versus Ultrasound Guided Serratus Anterior Plane Block Regarding Analgesia Post Modified Radical Mastectomy


Sponsor

Kholoud Usama

Enrollment

100 participants

Start Date

Mar 3, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical trial is to compare Ultrasound Guided Erector Spinae and Ultrasound Guided Serratus Anterior Plane Block post Modified Radical Mastectomy in adult females. the main questions it aims to answer are: * Which of the two blocks has a better analgesic effect? * Which of the two blocks is safer as regards inducing a pneumothorax and affecting the hemodynamics? Participants: * Will be divided into two groups after signing the informed consent. * After being anesthetized and before surgical incision; the blocks will be given to the patient. * Lung Ultrasound will be done for each patient to rule out pnemothorax once before the surgery and another after the end of surgery while the patient is being anesthetized. * Patients that will experience pneuomothorax will be excluded from the study, and will be treated according to its size. * Follow up of the patient for 24 hours postoperative to record the VAS score continuously, with giving increments of pethidine intravenously to relief pain.


Eligibility

Sex: FEMALEMin Age: 21 YearsMax Age: 65 Years

Inclusion Criteria3

  • ASA Physical Status II, or III.
  • Age 21 - 65 years.
  • Female gender

Exclusion Criteria6

  • ASA IV, V, VI.
  • Infection at site of block.
  • Coagulopathy, or patients on antiplatelets, or anticoagulants.
  • Previous anesthetic allergy to bupivacaine.
  • Distant organ metastasis.
  • Male gender.

Interventions

PROCEDUREUnilateral Erector Spinae group

On injecting 30 ml of bupivacaine 0.25% with 20 mcg Dexamedetomidine into the interfacial plane below erector spinae; a manifest linear pattern will be visualized uplifting the muscle.

PROCEDUREUnilateral Serratus Anterior group

Once the needle will be in perfect position, confirmed by hydro-dissection on injecting 2-3 ml of normal saline, then 30 ml of bupivacaine 0.25% with 20 mcg Dexamedetomidine.


Locations(1)

Faculty of Medicine, Ain-Shams University

Cairo, Waili, Egypt

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NCT06947330


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