RecruitingNot ApplicableNCT06956040

Involvement of General Practitioners in Lung Cancer Screening


Sponsor

Assistance Publique - Hôpitaux de Paris

Enrollment

500 participants

Start Date

Jun 2, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The main objective is to evaluate the adherence of smoking patients to lung cancer screening by low-dose CT scan, when proposed by the general practitioner.


Eligibility

Min Age: 50 YearsMax Age: 74 Years

Inclusion Criteria4

  • Adults aged 50-74
  • Active smoker or weaned smoker for less than 15 years, of at least 20 pack-years
  • Affiliation with a social security scheme or CMU (beneficiary or beneficiary entitled)
  • Written informed consent prior to study participation

Exclusion Criteria12

  • History of lung cancer
  • Thoracic CT scan performed within the previous year
  • year follow-up not possible
  • Inability to travel independently to Hôpital Cochin or Hôpital Bichat for scans
  • People with severe co-morbidities contraindicating exploration and/or management of lung cancers
  • People in poor general health (=PS2 and above)
  • People with a history of cancer under active surveillance by thoracic computed tomography (CT and PET scans)
  • People with rest dyspnea (=mMRC4)
  • Recent weight loss, altered general condition or hemoptysis, raising suspicion of progressive lung cancer
  • Signs of respiratory infection (fever, productive cough)
  • Patients under guardianship, curatorship or protected adults
  • Inability to give free written informed consent prior to study participation

Interventions

PROCEDURELow-dose computed tomography of the chest

Baseline low dose Ct acquisition, then at 1 year to depict suspicious lung nodules


Locations(1)

Hôpital Cochin

Paris, France

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NCT06956040


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