RecruitingNot ApplicableNCT06957964

Prophylactic Negative Pressure Wound Therapy in Laparotomy Wounds: A Randomized Clinical Trial


Sponsor

Dr Hamail Khanum

Enrollment

70 participants

Start Date

Mar 25, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

Total 70 participants meeting selection criteria will be enrolled in the study from operational theatre. They will be randomly divided in two groups by using lottery method. In group A, Negative Pressure Wound Therapy will be applied at end of procedure. In group B, no Negative Pressure Wound Therapy will be placed. They will be shifted to post-surgical wad for 72 hours and then will be discharged with prescription of standard antibiotics and will be followed-up in OPD for 30 days. If patient will develop surgical site wound infection, then it will be noted. If infection will not be cured with antibiotics course, then re-operation will be done. Patients complications will be managed as per hospital protocol. All this information will be recorded in proforma.


Eligibility

Min Age: 20 YearsMax Age: 70 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Negative Pressure Wound Therapy and a drug called Standard Antibiotic Treatment for people with infection prevention, negative pressure wound therapy, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 20 Years to 70 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERNegative Pressure Wound Therapy

Negative Pressure Wound Therapy is an intervention in which a suction is applied at applied thus creating a negative pressure which not only removes any exudate but also aids in formation of granulation tissue. NPWT is provided along with empirical prophylactic antibiotics

DRUGStandard Antibiotic Treatment

According to hospital antibiogram, empirical antibiotics are given prophylactically


Locations(1)

Gulab Devi Hospital Lahore

Lahore, Punjab Province, Pakistan

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NCT06957964


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