RecruitingNCT06965335

Early-Onset Colorectal Cancer: An Observational Retrospective and Prospective Multicenter Study

Early-Onset Colorectal Cancer: An Observational Retrospective and Prospective Multicenter Study - (The HEBE Study)


Sponsor

Niguarda Hospital

Enrollment

20 participants

Start Date

Apr 17, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

Observational, retrospective and prospective multicentric Italian study of patients diagnosed with colorectal cancer between age 18-40, aiming at underpinning the biology of vEO-CRC, including colibactin as well as a broader proteo-genomic characterization, to identify potential new therapeutic targets specifically directed to this peculiar subset of patients.


Eligibility

Min Age: 18 YearsMax Age: 40 Years

Plain Language Summary

Simplified for easier understanding

This study is looking at colorectal cancer (bowel cancer) that occurs in younger adults (18–40 years old) — called early-onset — to understand what makes it different from cancer diagnosed in older adults (over 60), using stored tissue samples and patient data. **You may be eligible if...** - You have been diagnosed with colorectal cancer and were either 18–40 years old at the time, or diagnosed after age 60 - You are willing to sign a consent form (if still alive) - Tumor tissue samples are available from your surgery or biopsy **You may NOT be eligible if...** - Your cancer was diagnosed between ages 41 and 60 - No tissue samples are available Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BIOLOGICALBIOLOGICAL STUDY aiming at describing clinicophatological features of EO-CRC vs SO-CRC

Description of clinicophatological features of EO-CRC vs SO-CRC


Locations(1)

ASST Grande Ospedale Metropolitano Niguarda

Milan, Milano, Italy

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NCT06965335


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