RecruitingNCT06967207

Electrical Impedance Tomography-Based Prognostic Model for ARDS

Electrical Impedance Tomography-Based Prognostic Model for ARDS: A Multicenter, Prospective, Observational Study

Sponsor

XiaoJing Zou,MD

Enrollment

625 participants

Start Date

Apr 15, 2025

Study Type

OBSERVATIONAL

Conditions

Acute Respiratory Distress Syndrome (ARDS)

Summary

This multicenter, prospective, observational study aims to develop and validate an EIT-based prognostic model for ARDS. By focusing on the pathophysiological characteristics of ARDS and the causes of ventilator-induced lung injury, the investigators intend to establish a prognostic model that reveals lung injury and heterogeneity, enabling risk stratification and guiding individualized treatment.

Eligibility

Min Age: 18 YearsMax Age: 80 Years

Inclusion Criteria2

Meet the new 2023 ARDS global definition;
Age 18-80 years

Exclusion Criteria10

Expected death within 24 hours of screening;
Metastatic cancer (active malignancy with distant metastases);
Severe psychiatric disorders;
Pregnancy or postpartum status;
Pneumothorax or moderate to large pleural effusion without adequate drainage;
Chronic respiratory failure;
Patients with pulmonary embolism or pulmonary hypertension;
Heart failure patients: EF <50% or NYHA class III or IV;
Patient/family refusal to participate;
Participation in another interventional trial within 3 months prior to enrollment