Effect of Trendelenburg Positioning on Anesthesia-Induced Hypotension in Elderly Patients
Effect of Trendelenburg Positioning on Anesthesia-Induced Hypotension in Elderly Patients: A Randomized Controlled Clinical Trial
Zhejiang Cancer Hospital
168 participants
May 16, 2025
INTERVENTIONAL
Conditions
Summary
This study investigated the effect of Trendelenburg position on preventing post-induction hypotension in elderly patients undergoing abdominal surgery with general anesthesia. The patients will receive the 10° Trendelenburg position or supine position during anesthesia induction. The primary outcome is the area under a mean arterial pressure (MAP) below 65 mm Hg within the first 15 minutes during anesthesia induction.
Eligibility
Inclusion Criteria4
- patients aged 65-90 years
- scheduled for abdominal surgery with general anesthesia
- expected to have continuous radial arterial pressure monitoring
- American Society of Anesthesiologists (ASA) physical status I to III
Exclusion Criteria6
- contraindications or failure of radial arterial catheterization
- expected possible difficult airway
- non-sinus rhythm
- increased intracranial pressure
- patients at high risk of regurgitation or aspiration
- inability to provide consent
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Interventions
After the loss of consciousness during general anesthesia, the 10° Trendelenburg position is adopted.
After the loss of consciousness during general anesthesia, the Supine Horizontal Position is adopted.
Locations(1)
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NCT06968091