Effect of ExoBDNF Lactic Acid Bacteria Supplement on Cognitive Functions, Sleep and Psychological

Exclusion Criteria9

• Subjects who are expected to be or have been confirmed to be pregnant (medical history).
• Subjects with gallbladder disease, gastrointestinal disease, gout, porphyria, or a history of gastric weight control surgery.
• Subjects with high blood pressure (≥160/100 mmHg after resting for 10 minutes) or taking diuretics.
• Subjects with heart disease, hepatorenal insufficiency, hyperthyroidism or hypothyroidism, Cushing's syndrome, malignant tumors, or any other disease that may affect the results of the study.
• Subjects with severe hearing or visual impairment that makes it impossible to perform examinations and assessments.
• Subjects with any history of brain surgery, penetrating, neurovascular, infectious or other severe brain injury, epilepsy or other major neurological abnormalities, such as traumatic brain injury with loss of consciousness for more than 24 hours, or memory loss after head trauma for more than 7 days were excluded.
• Subjects with intellectual disabilities.
• Subjects who had consumed probiotics or were expected to consume probiotics within 2 weeks before the screening visit.
• Subjects who had participated in or were expected to participate in clinical trials within 4 weeks before the screening visit.