RecruitingNot ApplicableNCT06968390

Accelerated TMS for Perinatal Depression

Perinatal Accelerated iTBS Neuromodulation Therapy


Sponsor

Brigham and Women's Hospital

Enrollment

24 participants

Start Date

Aug 5, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

We are studying a treatment for depression called accelerated Transcranial Magnetic Stimulation (TMS) among pregnant and postpartum individuals. TMS is a focal, non-invasive form of brain stimulation that is cleared by the Food and Drug Administration for depression. Typically, traditional TMS involves daily treatments for 6-8 weeks. In this study, we will offer an accelerated form of TMS that involves multiple daily treatments for 5 days.


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 55 Years

Plain Language Summary

Simplified for easier understanding

This study is testing an accelerated form of transcranial magnetic stimulation (TMS) — a non-invasive brain treatment using magnetic pulses — to help people experiencing depression during pregnancy or in the first year after giving birth. **You may be eligible if...** - You are between 18 and 55 years old - You are between 14 and 34 weeks pregnant, OR within one year of delivery - You are experiencing significant depression symptoms - You have not found relief from standard treatments, or prefer a non-medication option **You may NOT be eligible if...** - You are past 34 weeks of pregnancy (risk of not completing the study before delivery) - You have a metal implant in or near your head (such as a cochlear implant or certain surgical clips) - You have a history of epilepsy or seizures - You have bipolar disorder or psychosis - You are under 18 or over 55 Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICETranscranial Magnetic Stimulation

Non-invasive form of brain stimulation.


Locations(1)

Brigham and Women's Hospital

Boston, Massachusetts, United States

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NCT06968390


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