RecruitingNot ApplicableNCT06969833

Prospective Clinico-biological Database of Patients With Ovarian and/or Peritoneal and/or Fallopian Tube Carcinoma

Study of Prognostic Factors Associated With Overall Survival in Patients Initially Treated for Advanced Ovarian and/or Peritoneum and/or Fallopian Tubes Carcinoma: Analysis Using a Prospective Clinico-Biological Database


Sponsor

Centre Oscar Lambret

Enrollment

371 participants

Start Date

Jun 27, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

Cancer of the ovary and/or peritoneum and/or fallopian tube have a very poor prognosis, and require the implementation of collaborative research tools and new innovative therapies. The main objective of this study is to implement prognostic model of overall survival on patients included prospectively as part of the initial treatment of advanced ovarian and/or peritoneum, and/or fallopian tubes carcinoma (this cohort corresponds to the "Turquoise" care pathway of the Oscar Lambret Center) regardless of the treatment carried out,, integrating both patient's and tumor's characteristics. A clinical and biological database is implemented for this purpose. 371 patients will be recruited over a 5-year period at the Oscar Lambret Center. The active participation of each patient will be 2 years (from the date of inclusion until the end of study participation, defined by the date of the last intervention specific to the research), then the data from standard care and survival data will be collected until the last follow-up of the last patient, 2 years after the last inclusion.


Eligibility

Sex: FEMALEMin Age: 18 Years

Inclusion Criteria5

  • Patient aged 18 or over
  • Informed consent warranted
  • Patient affiliated to a social security regimen
  • Suspected or confirmed diagnosis of advanced and invasive ovarian cancer and/or primary peritoneal cancer and/or fallopian tube cancer (IIB to IV FIGO stages)
  • Inclusion during standard care at the Oscar Lambret Centre, from diagnosis to the day of surgery

Exclusion Criteria2

  • Patient deprived of liberty or under curatorship or guardianship
  • Refusal to participate

Interventions

OTHERConstitution of a biological collection

* Left-over tissue samples (tumor tissue of different nature) frozen and secured in paraffin, and derived from standard care, are collected at study entrance until the end of oncologic treatment. * One blood sample of 28mL is collected at time of inclusion

OTHERAssessment of Quality of Life and level of anxiety/depression

Questionnaires QLQ-C30, OV-28 and HADS are completed by the patients at inclusion, after 3 and 6 cycles of systemic treatment, and every 3 months up to 2 years after inclusion


Locations(1)

Centre Oscar Lambret

Lille, France

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NCT06969833


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