RecruitingNot ApplicableNCT06969833

Prospective Clinico-biological Database of Patients With Ovarian and/or Peritoneal and/or Fallopian Tube Carcinoma

Study of Prognostic Factors Associated With Overall Survival in Patients Initially Treated for Advanced Ovarian and/or Peritoneum and/or Fallopian Tubes Carcinoma: Analysis Using a Prospective Clinico-Biological Database


Sponsor

Centre Oscar Lambret

Enrollment

371 participants

Start Date

Jun 27, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

Cancer of the ovary and/or peritoneum and/or fallopian tube have a very poor prognosis, and require the implementation of collaborative research tools and new innovative therapies. The main objective of this study is to implement prognostic model of overall survival on patients included prospectively as part of the initial treatment of advanced ovarian and/or peritoneum, and/or fallopian tubes carcinoma (this cohort corresponds to the "Turquoise" care pathway of the Oscar Lambret Center) regardless of the treatment carried out,, integrating both patient's and tumor's characteristics. A clinical and biological database is implemented for this purpose. 371 patients will be recruited over a 5-year period at the Oscar Lambret Center. The active participation of each patient will be 2 years (from the date of pre-registration until the end of study participation, defined by the date of the last intervention specific to the research), then the data from standard care and survival data will be collected until the last follow-up of the last patient, 2 years after the last pre-registration.


Eligibility

Sex: FEMALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is building a long-term medical database of patients with advanced ovarian cancer, peritoneal cancer, or fallopian tube cancer, to better understand how the disease progresses and to improve future treatment strategies. **You may be eligible if...** - You are 18 or older - You have a suspected or confirmed diagnosis of advanced ovarian, primary peritoneal, or fallopian tube cancer (stage IIB through IV) - You are receiving care at Oscar Lambret Centre, from your initial diagnosis through to surgery - You are enrolled in the national social security system **You may NOT be eligible if...** - You are under legal protection measures that would prevent you from giving consent (such as guardianship) - You do not wish to participate Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERConstitution of a biological collection

* Left-over tissue samples (tumor tissue of different nature) frozen and secured in paraffin, and derived from standard care, are collected at study entrance until the end of oncologic treatment. * One blood sample of 28mL is collected once inclusion is confirmed

OTHERAssessment of Quality of Life and level of anxiety/depression

Questionnaires QLQ-C30, OV-28 and HADS are completed by the patients after pre-registration, then after 3 and 6 cycles of systemic treatment, and every 3 months up to 2 years after pre-registration


Locations(1)

Centre Oscar Lambret

Lille, France

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NCT06969833


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