RecruitingPhase 2NCT06971224

NADream: Effects of Nicotinamide Adenine Dinucleotide Supplementation on Sleep Quality in Healthy Individuals

NADream: Effects of Nicotinamide Adenine Dinucleotide Supplementation on Sleep Quality in Healthy Individuals: A Randomized Controlled Pilot Study


Sponsor

Haukeland University Hospital

Enrollment

16 participants

Start Date

Oct 13, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to evalue the effects of nicotinamide adenine dinucleotide (NAD) supplementation (nicotinamide riboside (NR) form) on sleep in healthy adults compared to a placebo. NAD is important for brain health and energy balance and a proposed explanation for its effect on sleep is that NAD supplementation restores the neurophysiological capacity of the brain to 'rest' during sleep. If this is the case, we expect the administration to result in improvements in sleep quality (and most likely sleep quantity) compared to placebo. Participants will receive either NAD supplementation or a placebo and their sleep will be measured to detect any differences between the two groups.


Eligibility

Min Age: 40 YearsMax Age: 60 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Nicotinamide Riboside (NR) and Placebo for people with sleep. The study is currently recruiting participants at 1 location. People eligible for this study include aged 40 Years to 60 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIETARY_SUPPLEMENTNicotinamide Riboside (NR)

2000 mg NR daily.

OTHERPlacebo

Placebo tablet identical in taste, shape and appearance to NR tablets.


Locations(1)

Haukeland University Hospital

Bergen, Norway

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NCT06971224


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