A Prospective Clinical Study to Evaluate the Safety and Effectiveness of Pulmonary Vein Isolation Plus Box Isolation of Fibrotic Areas With the Globe® Pulsed Field System for Treating Patients With Symptomatic Paroxysmal or Persistent Atrial Fibrillation

This study is testing a new technology — the Globe Pulsed Field System — for treating atrial fibrillation (an irregular heartbeat) using a type of energy called pulsed field ablation, which targets and destroys the heart tissue causing the abnormal rhythm. **You may be eligible if...** - You have been diagnosed with paroxysmal (comes and goes) or persistent atrial fibrillation with recurring symptoms - At least one anti-arrhythmic medication has not worked or caused side effects **You may NOT be eligible if...** - You have had atrial fibrillation continuously for more than 12 months - Your atrial fibrillation is caused by something reversible (e.g., thyroid disease, recent surgery) - You had a stroke or blood clot event in the past 6 months - You had a heart attack, stent, or cardiac surgery in the last 3–6 months - You have had a previous ablation or surgery on the left side of your heart - You have a pacemaker or other implanted heart device - Your BMI is over 40 or your heart pumping function is significantly reduced Talk to your doctor to see if this trial is right for you.