Non-Narcotic Pain Control After ACL Reconstruction
The Cleveland Clinic
30 participants
Jul 15, 2025
INTERVENTIONAL
Conditions
Summary
This is a double-blind randomized controlled trial of standard of care therapy, either oral ketorolac (experimental group) or oral oxycodone (control group) to demonstrate efficacy in reducing the percentage of narcotic doses taken and documenting the number of patients with no exposure to any narcotics (take zero oxycodone) after undergoing primary knee ACL reconstruction outpatient surgery.
Eligibility
Inclusion Criteria5
- Provision of signed and dated informed consent form
- Stated willingness to comply with all study procedures and availability for the duration of the study
- Male or female, aged 15-55 years
- Primary Autograft ACL surgery
- Ability to take oral medication and willingness to patriciate in a virtual 1 and 2 week follow-up pill counts
Exclusion Criteria5
- Provision of signed and dated informed consent form
- Stated willingness to comply with all study procedures and availability for t the duration of the study
- Male or female, aged 15-55 years
- Primary Autograft ACL surgery
- Ability to take oral medication and willingness to patriciate in a virtual 1 and 2 week follow-up pill counts
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Interventions
• Cohort Group 1 (Experimental): ketorolac 10mg with rescue medication oxycodone 5mg All patients will be given acetaminophen
Patients will be randomized to either Ketorolac or Oxycodone
Locations(3)
View Full Details on ClinicalTrials.gov
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NCT06973785