RecruitingPhase 3NCT06973785

Non-Narcotic Pain Control After ACL Reconstruction

Sponsor

The Cleveland Clinic

Enrollment

30 participants

Start Date

Jul 15, 2025

Study Type

INTERVENTIONAL

Conditions

ACL Injuries ACL - Anterior Cruciate Ligament Rupture

Summary

This is a double-blind randomized controlled trial of standard of care therapy, either oral ketorolac (experimental group) or oral oxycodone (control group) to demonstrate efficacy in reducing the percentage of narcotic doses taken and documenting the number of patients with no exposure to any narcotics (take zero oxycodone) after undergoing primary knee ACL reconstruction outpatient surgery.

Eligibility

Min Age: 15 YearsMax Age: 55 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Ketorolac and dispense of study drug for people with acl - anterior cruciate ligament rupture and acl injuries. The study is currently recruiting participants at 3 locations. People eligible for this study include aged 15 Years to 55 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGdispense of study drug

• Cohort Group 1 (Experimental): ketorolac 10mg with rescue medication oxycodone 5mg All patients will be given acetaminophen

DRUGKetorolac

Patients will be randomized to either Ketorolac or Oxycodone

Locations(3)

Cleveland Clinic Coral Springs

Coral Springs, Florida, United States

Cleveland clinic sports medicine

Garfield, Ohio, United States

Cleveland Clinic

Strongsville, Ohio, United States

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NCT06973785

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