ACL - Anterior Cruciate Ligament Rupture Clinical Trials

7 recruitingLast updated: May 13, 2026

There are 7 actively recruiting acl - anterior cruciate ligament rupture clinical trials across 8 countries. Studies span Not Applicable, Phase 3. Top locations include Coral Springs, Florida, United States, Garfield, Ohio, United States, Hamilton, Ontario, Canada. Updated daily from ClinicalTrials.gov.


ACL - Anterior Cruciate Ligament Rupture Trials at a Glance

7 actively recruiting trials for acl - anterior cruciate ligament rupture are listed on ClinicalTrialsFinder across 6 cities in 8 countries. The largest study group is Not Applicable with 5 trials, with the heaviest enrollment activity in Coral Springs, Garfield, and Hamilton. Lead sponsors running acl - anterior cruciate ligament rupture studies include GCS Ramsay Santé pour l'Enseignement et la Recherche, Hvidovre University Hospital, and European University Cyprus.

Browse acl - anterior cruciate ligament rupture trials by phase

Treatments under study

About ACL - Anterior Cruciate Ligament Rupture Clinical Trials

Looking for clinical trials for ACL - Anterior Cruciate Ligament Rupture? There are currently 7 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new ACL - Anterior Cruciate Ligament Rupture trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about ACL - Anterior Cruciate Ligament Rupture clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 17 of 7 trials

Recruiting

Do Patients With ACL Tears Demonstrate Weakness of the Soleus Muscle?

ACL InjuryACL TearACL - Anterior Cruciate Ligament Rupture
University of Liverpool55 enrolled1 locationNCT06235736
Recruiting
Not Applicable

Clinical-randomized Trial of the Effect of Rehabilitation Therapy Using Strength and Blood Flow Restriction Training on Muscular Fitness and Regeneration After Anterior Cruciate Ligament Reconstruction

ACL - Anterior Cruciate Ligament Rupture
University Hospital, Bonn30 enrolled1 locationNCT07043569
Recruiting
Not Applicable

Comparison of Arthrogenic Muscle Inhibition (AMI) After ACL Reconstruction in Patients With Conventional Rehabilitation or Conventional Rehabilitation Combined With Digital Therapy

ACL - Anterior Cruciate Ligament Rupture
GCS Ramsay Santé pour l'Enseignement et la Recherche448 enrolled1 locationNCT07030764
Recruiting
Not Applicable

Optimizing Graft Selection for ACL Reconstruction

ACL - Anterior Cruciate Ligament Rupture
Hvidovre University Hospital150 enrolled1 locationNCT05342441
Recruiting
Phase 3

Non-Narcotic Pain Control After ACL Reconstruction

ACL InjuriesACL - Anterior Cruciate Ligament Rupture
The Cleveland Clinic30 enrolled3 locationsNCT06973785
Recruiting
Not Applicable

Conservative Treatment With Blood Flow Restriction in Patients With Total ACL Rupture. "Randomized Clinical Trial"

ACLACL - Anterior Cruciate Ligament Rupture
European University Cyprus20 enrolled2 locationsNCT06727344
Recruiting
Not Applicable

Soft-tissue Quadriceps Autograft ACL-reconstruction in the Skeletally-immature vs. Hamstrings

ACL - Anterior Cruciate Ligament Rupture
McMaster University352 enrolled6 locationsNCT03896464