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RecruitingPhase 2NCT06976658

Glucokinase Activator in Monogenic Diabetes

Evaluating a Novel, Allosteric Glucokinase Activator in Monogenic Diabetes Secondary to Inactivating Glucokinase Mutations: a Randomised, Cross-over Trial

Sponsor

Chinese University of Hong Kong

Enrollment

44 participants

Start Date

Apr 30, 2025

Study Type

INTERVENTIONAL

Conditions

Diabetes MellitusMonogenic Diabetes

Summary

Evaluating a novel, allosteric glucokinase activator in monogenic diabetes secondary to inactivating glucokinase mutations: a randomised, cross-over trial

Eligibility

Min Age: 18 YearsMax Age: 74 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Dorzagliatin and a drug called matched placebo for people with diabetes mellitus and monogenic diabetes. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 74 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGDorzagliatin

Dorzagliatin 50mg bd

DRUGmatched placebo

matched placebo

Locations(1)

3M, Diabetes and Endocrine Research Center

Hong Kong, Hong Kong

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NCT06976658

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