Diabetes Mellitus Clinical Trials

197 recruiting

Diabetes Mellitus Trials at a Glance

760 actively recruiting trials for diabetes mellitus are listed on ClinicalTrialsFinder across 6 cities in 78 countries. The largest study group is Not Applicable with 316 trials, with the heaviest enrollment activity in Boston, Philadelphia, and Chicago. Lead sponsors running diabetes mellitus studies include Novo Nordisk A/S, Eli Lilly and Company, and Mayo Clinic.

Browse diabetes mellitus trials by phase

Treatments under study

About Diabetes Mellitus Clinical Trials

Looking for clinical trials for Diabetes Mellitus? There are currently 197 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Diabetes Mellitus trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Diabetes Mellitus clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 760 trials

Recruiting
Not Applicable

The eHealth Diabetes Remission Trial

Diabetes Mellitus, Type 2
Umeå University106 enrolled3 locationsNCT05491005
Recruiting

Genetic Studies of Insulin and Diabetes

Diabetes MellitusSevere Insulin Resistance
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)1,200 enrolled1 locationNCT00001987
Recruiting

The Real-World Control-IQ Glycemic Control and Quality of Life Study in Type 1 Diabetes in France

Diabetes Mellitus, Type 1
Tandem Diabetes Care, Inc.350 enrolled21 locationsNCT07211126
Recruiting
Phase 4

Effect of Early Combination Antihyperglycemic Treatment on Metabolic Control in Individuals With Type 2 Diabetes

Type 2 Diabetes Mellitus (T2DM)
University Medical Centre Ljubljana90 enrolled1 locationNCT06613854
Recruiting

POLUS: Description of the Effectiveness and Tolerability of Luseogliflozin in Patients With Type 2 Diabetes.

Type 2 Diabetes Mellitus
Servier Russia300 enrolled1 locationNCT07433192
Recruiting
Phase 3

EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

Cardiovascular DiseasesHypertensionDiabetes Mellitus, Type 2
Boehringer Ingelheim11,800 enrolled1152 locationsNCT07064473
Recruiting
Phase 1

A Clinical Study Comparing the Relative Bioavailability and Safety of SHR-3167 Injection

Diabetes Mellitus
Jiangsu HengRui Medicine Co., Ltd.60 enrolled1 locationNCT07489482
Recruiting
Not Applicable

Implementing Scalable, PAtient-centered, Team-based, Technology-enabled Care for Adults With Type 2 Diabetes (iPATH)

Diabetes Mellitus, Type 2
Stanford University119,680 enrolled4 locationsNCT06251323
Recruiting

Mixed Methods Study of Health-Related Social Needs in African American Adults With Chronic Kidney Disease and Type 2 Diabetes Mellitus

Chronic Kidney DiseasesDiabetes Mellitus, Type 2Diabetic Nephropathy Type 2 - Uncontrolled
Medical College of Wisconsin330 enrolled1 locationNCT05692388
Recruiting
Not Applicable

The Use of Ultrasound Detection of Lipohypertrophy to Improve Glycemic Control

Diabetes MellitusLipohypertrophy
University of British Columbia100 enrolled1 locationNCT05377268
Recruiting
Phase 2

Glucokinase Activator in Monogenic Diabetes

Diabetes MellitusMonogenic Diabetes
Chinese University of Hong Kong44 enrolled1 locationNCT06976658
Recruiting
Not Applicable

Impact of Behavioural Modification Working Toolkit Among Women With Gestational Diabetes Mellitus and Hypertension

Gestational Diabetes Mellitus in PregnancyHypertension ,Pregnancy
University of the Punjab220 enrolled2 locationsNCT07551011
Recruiting
Phase 2

Regulation of Endogenous Glucose Production by Central KATP Channels

Diabetes MellitusGlucose Metabolism Disorders
Albert Einstein College of Medicine100 enrolled1 locationNCT03540758
Recruiting
Phase 2

A Study of the Effect of ZT-01 on Night-time Hypoglycemia in Type 1 Diabetes

Type 1 Diabetes Mellitus With Hypoglycemia
Zucara Therapeutics Inc.186 enrolled46 locationsNCT05762107
Recruiting

Prevalence, Incidence and Risk Signature of Chronic Kidney Disease in Sub-Saharan Africa

ObesityCardiovascular DiseasesChronic Kidney Diseases+8 more
Swiss Tropical & Public Health Institute1,200 enrolled1 locationNCT05881447
Recruiting

Early Tracking of Childhood Health Determinants (ETCHED) Study

Diabetes MellitusObesityFatty Liver
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)1,500 enrolled1 locationNCT03481829
Recruiting
Phase 3

A Study to Investigate Efficacy and Safety of Teplizumab Compared With Placebo in Participants 1 to 25 Years of Age With Stage 3 Type 1 Diabetes

Type 1 Diabetes Mellitus
Sanofi723 enrolled141 locationsNCT07088068
Recruiting
Not Applicable

Goal Commitment and Proactive Health Behavior in Chronic Disease Patients

Diabetes MellitusHypertensionDyslipidemia
Xiong Juyang600 enrolled1 locationNCT07552571
Recruiting
Phase 3

AMAZE 2: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight

Diabetes MellitusObesityOverweight
Novo Nordisk A/S630 enrolled73 locationsNCT07533175
Recruiting
Not Applicable

Culturally Tailored Program for Food-Insecure Adults: SPICE-D

Type 2 Diabetes Mellitus (T2D)
Wake Forest University Health Sciences25 enrolled1 locationNCT07361341