RecruitingNCT06978803

HYEEG Discourse in Psychosis: A Neurobehavioural Study


Sponsor

Douglas Mental Health University Institute

Enrollment

110 participants

Start Date

Jan 16, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

This multimodal study explores the mechanisms underlying social dysfunction in individuals with schizophrenia. It focuses on the relationship between disorganized communication and social interaction, aiming to identify measurable markers of disorganized communication and link them to clinical symptoms and social functioning. Key Research Questions: How do neural and behavioural synchrony contribute to social impairments in schizophrenia? What roles do interbrain synchrony, motor imitation, reaction time, and verbal coherence play in disorganized communication? Participants will: 1. Engage in structured and semi-structured real-time social interactions while undergoing dual-brain electroencephalogram (EEG) hyperscanning to measure neural and behavioural activity. 2. Perform nonverbal tasks such as motor imitation and reaction time assessments to investigate coordination and behavioural synchrony patterns. 3. Participate in a clinical interview that evaluates verbal production, thought coherence, and speech organization. By combining these assessments, the study aims to advance our understanding of how social and communication impairments manifest in schizophrenia. The findings will contribute to developing improved diagnostic tools and targeted interventions, ultimately supporting patients in achieving better social functioning and quality of life.


Eligibility

Min Age: 18 YearsMax Age: 60 Years

Plain Language Summary

Simplified for easier understanding

This study is examining how people with early psychosis (schizophrenia or schizoaffective disorder) communicate in conversation, using brain activity recordings (EEG) and speech analysis. The goal is to better understand the brain and language patterns associated with psychosis to improve early diagnosis and treatment. **You may be eligible if...** - You are between 18 and 60 years old - You speak English or French - You have been diagnosed with schizophrenia or schizoaffective disorder within the last 5 years - Your diagnosis was made by your treating psychiatrist **You may NOT be eligible if...** - Your primary diagnosis is alcohol or drug addiction (though having both psychosis and substance use issues is acceptable) - You have a serious medical condition that could explain your psychotic symptoms - You have a neurological disorder affecting speech - Your IQ is below 70 or you have been diagnosed with autism or another pervasive developmental disorder Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

Douglas Mental Health University Institute

Montreal, Quebec, Canada

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NCT06978803


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