RecruitingPhase 3NCT06979453

A Study to Evaluate the Efficacy, Safety, and Drug Levels of Deucravacitinib (BMS-986165) in Adolescent Participants With Moderate to Severe Plaque Psoriasis

A Multicenter, Randomized, Double-blind, Placebo-controlled Phase 3 Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Deucravacitinib in Adolescent Participants (12 Years to Less Than 18 Years) With Moderate to Severe Plaque Psoriasis

Sponsor

Bristol-Myers Squibb

Enrollment

366 participants

Start Date

Dec 3, 2025

Study Type

INTERVENTIONAL

Conditions

Plaque Psoriasis

Summary

The purpose of this study is to evaluate the efficacy, safety, and drug levels of Deucravacitinib (BMS-986165) in adolescent participants with moderate to severe plaque psoriasis

Eligibility

Min Age: 12 YearsMax Age: 17 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Deucravacitinib and Placebo for people with plaque psoriasis. The study is currently recruiting participants at 123 locations. People eligible for this study include aged 12 Years to 17 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGDeucravacitinib

Specified dose on specified days

OTHERPlacebo

Specified dose on specified days

Locations(129)

Local Institution - 0261

Birmingham, Alabama, United States

Local Institution - 0041

Birmingham, Alabama, United States

Local Institution - 0053

Phoenix, Arizona, United States

Local Institution - 0025

Fountain Valley, California, United States

Center For Dermatology Clinical Research, Inc.

Fremont, California, United States

Dermatology Research Associates

Los Angeles, California, United States

Northridge Clinical Trials

Northridge, California, United States

Local Institution - 0077

Sacramento, California, United States

Golden State Dermatology - Walnut Creek - Ygnacio Valley Road

Walnut Creek, California, United States

Paradigm Clinical Research, LLC

Wheat Ridge, Colorado, United States

Local Institution - 0021

Clearwater, Florida, United States

Life Clinical Trials

Margate, Florida, United States

Skin Research of South Florida

Miami, Florida, United States

Wellness Clinical Research

Miami Lakes, Florida, United States

MOORE Clinical Research, Inc. d/b/a TrueBlue Clinical Research

Tampa, Florida, United States

USF Health

Tampa, Florida, United States

Dermatology Affiliates Research Institute

Atlanta, Georgia, United States

Advanced Medical Research, PC.

Sandy Springs, Georgia, United States

Local Institution - 0271

Ammon, Idaho, United States

Dawes Fretzin Clinical Research Group, LLC

Indianapolis, Indiana, United States

Kentucky Advanced Medical Research LLC

Murray, Kentucky, United States

Local Institution - 0202

Metairie, Louisiana, United States

Dermatology and Skin Cancer Specialists, LLC

Rockville, Maryland, United States

Kuchnir Dermatology & Dermatologic Surgery

Milford, Massachusetts, United States

Local Institution - 0095

Detroit, Michigan, United States

Henry Ford Medical Center

Detroit, Michigan, United States

Local Institution - 0233

Columbia, Missouri, United States

Local Institution - 0278

Columbia, Missouri, United States

Local Institution - 0266

Lee's Summit, Missouri, United States

JDR Dermatology Research

Las Vegas, Nevada, United States

Local Institution - 0283

Clifton, New Jersey, United States

Local Institution - 0281

Robbinsville, New Jersey, United States

Local Institution - 0273

Brooklyn, New York, United States

Local Institution - 0205

New York, New York, United States

Local Institution - 0166

The Bronx, New York, United States

Local Institution - 0234

Hickory, North Carolina, United States

Apex Clinical Research Center - Canton

Canton, Ohio, United States

Apex Clinical Research Center

Lorain, Ohio, United States

Apex Clinical Research Center

Mayfield Heights, Ohio, United States

Paddington Testing Company

Philadelphia, Pennsylvania, United States

ObjectiveHealth - Goodlettsville Dermatology Research

Goodlettsville, Tennessee, United States

Local Institution - 0248

Nashville, Tennessee, United States

Texas Dermatology and Laser Specialists

San Antonio, Texas, United States

Local Institution - 0280

Southlake, Texas, United States

Local Institution - 0045

Norfolk, Virginia, United States

Frontier Derm Partners

Mill Creek, Washington, United States

Local Institution - 0264

Spokane, Washington, United States

Instituto de Neumonologia Y Dermatologia

Ciudad Autonoma de Buenos Aires, Buenos Aires, Argentina

Psoriahue

Ciudad Autonoma de Buenos Aires, Buenos Aires, Argentina

Centro de Investigaciones Médicas Tucuman

SAN M. de Tucuman, Tucumán Province, Argentina

CONEXA Investigacion Clinica S.A.

Buenos Aires, Argentina

Hospital Italiano de Buenos Aires

Buenos Aires, Argentina

Hospital de Niños Dr. Ricardo Gutiérrez

Buenos Aires, Argentina

Derma Internacional

Buenos Aires, Argentina

Cliniques universitaires Saint-Luc

Brussels, Bruxelles-Capitale, Région de, Belgium

Local Institution - 0210

Brussels, Bruxelles-Capitale, Région de, Belgium

UZ Gent

Ghent, Oost-Vlaanderen, Belgium

Centre Hospitalier Universitaire de Liège - Domaine Universitaire du Sart Tilman

Liège, Belgium

Local Institution - 0137

Salvador, Estado de Bahia, Brazil

Local Institution - 0182

Porto Alegre, Rio Grande do Sul, Brazil

Hospital Moinhos de Vento

Porto Alegre, Rio Grande do Sul, Brazil

Local Institution - 0140

Barretos, São Paulo, Brazil

Local Institution - 0163

Ribeirão Preto, São Paulo, Brazil

Local Institution - 0170

São Paulo, Brazil

Alberta Dermasurgery Centre

Edmonton, Alberta, Canada

Local Institution - 0164

Winnipeg, Manitoba, Canada

Skincare Studio

St. John's, Newfoundland and Labrador, Canada

DermEffects

London, Ontario, Canada

The Centre for Dermatology

Richmond Hill, Ontario, Canada

AvantDerm

Toronto, Ontario, Canada

Local Institution - 0240

Toronto, Ontario, Canada

Local Institution - 0142

Montreal, Quebec, Canada

Beijing Children's hospital, Capital Medical University

Beijing, Beijing Municipality, China

Peking University Third Hospital

Beijing, Beijing Municipality, China

Guangdong Province Dermatology Hospital

Guangzhou, Guangdong, China

The University of Hong Kong-Shenzhen Hospital

Shenzhen, Guangdong, China

The Affiliated Hospital of Hebei University of Engineering

Handan, Hebei, China

People's Hospital of Henan Province

Zhengzhou, Henan, China

Hunan Children's Hospital

Changsha, Hunan, China

Local Institution - 0265

Jinan, Shandong, China

Shanghai Skin Disease Hospital

Shanghai, Shanghai Municipality, China

Local Institution - 0228

Chengdu, Sichuan, China

The First People's Hospital of Hangzhou

Hangzhou, Zhejiang, China

Local Institution - 0225

Medellín, Antioquia, Colombia

Local Institution - 0124

Medellín, Antioquia, Colombia

Local Institution - 0167

Barranquilla, Atlántico, Colombia

Local Institution - 0125

Bogota, Cundinamarca, Colombia

Universitätsklinikum Münster

Münster, North Rhine-Westphalia, Germany

BAG Drs. Med. Quist PartG

Mainz, Rhineland-Palatinate, Germany

Charité Universitaetsmedizin Berlin - Campus Mitte

Berlin, Germany

Universitaetsklinikum Carl Gustav Carus Dresden

Dresden, Germany

Universitaetsklinikum Erlangen

Erlangen, Germany

Szegedi Tudományegyetem Szent-Györgyi Albert Klinikai Központ

Szeged, Csongrád megye, Hungary

Clinexpert Kft.

Budapest, Pest County, Hungary

Debreceni Egyetem Klinikai Kozpont

Debrecen, Hungary

Fondazione Policlinico Universitario Agostino Gemelli IRCCS - Università Cattolica del Sacro Cuore

Roma, Italy

Local Institution - 0238

Zapopan, Jalisco, Mexico

Local Institution - 0253

Mexico City, Mexico City, Mexico

Local Institution - 0155

Monterrey, Nuevo León, Mexico

Local Institution - 0259

Chihuahua City, Mexico

Local Institution - 0257

Mérida, Mexico

Local Institution - 0258

Toluca, Mexico

Local Institution - 0096

Veracruz, Mexico

Local Institution - 0177

Lublin, Lublin Voivodeship, Poland

FutureMeds - Targowek

Warsaw, Masovian Voivodeship, Poland

SPECDERM Poznanska sp.j.

Bialystok, Podlaskie Voivodeship, Poland

Local Institution - 0282

Gdansk, Pomeranian Voivodeship, Poland

"DERMED" Centrum Medyczne Sp. z o.o.

Lodz, Poland

ETYKA Osrodek Badan Klinicznych

Olsztyn, Poland

Klinika Ambroziak Dermatologia

Warsaw, Poland

Royalderm Agnieszka Nawrocka

Warsaw, Poland

Local Institution - 0254

Bayamón, Puerto Rico

Local Institution - 0008

Caguas, Puerto Rico

GCM Medical Group, PSC - Hato Rey Site

San Juan, Puerto Rico

Local Institution - 0174

Bucharest, Bucharest, Romania

Lotus-Med Tunari

Bucharest, Bucharest, Romania

Local Institution - 0213

Bucharest, Bucharest, Romania

Policlinica Providența

Iași, Romania

Centrul de Medicina de Familie

Iași, Romania

New Derm Clinical SRL

Timișoara, Romania

Hospital Sant Joan de Déu

Esplugues de Llobregat, Barcelona [Barcelona], Spain

Hospital de la Santa Creu i Sant Pau

Barcelona, Catalunya [Cataluña], Spain

Grupo Dermatológico y Estético Pedro Jaén S.A

Madrid, Spain

Hospital Universitario 12 de Octubre

Madrid, Spain

CHUS - Hospital Clinico Universitario

Santiago de Compostela, Spain

Chang Gung Memorial Hospital at Kaohsiung

Kaohsiung Niao Sung Dist, Kaohsiung, Taiwan

Kaohsiung Veterans General Hospital

Kaohsiung City, Taiwan

National Taiwan University Hospital

Taipei, Taiwan

Chang Gung Medical Foundation-Linkou Branch

Taoyuan, Taiwan

View Full Details on ClinicalTrials.gov

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NCT06979453

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