RecruitingNot ApplicableNCT06382051

Modifying PEST for Psoriatic Arthritis Screening

A Multicenter, Prospective, Study to Evaluate the Impact of Modifying the Validated Psoriasis Epidemiology Screening Tool (PEST) on the Potential Diagnosis of Psoriatic Arthritis in Adult Patients With Moderate-to-severe Plaque Psoriasis in Canada ("ScreenX")


Sponsor

Novartis Pharmaceuticals

Enrollment

502 participants

Start Date

Jan 23, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to assess the impact of adding two questions and pictures to the validated PEST on the potential diagnosis of PsA in participants with moderate-to-severe plaque PsO in Canada.


Eligibility

Min Age: 18 Years

Inclusion Criteria4

  • Moderate-to-severe plaque PsO patients who are candidates for bDMARDs, according to physician's clinical judgement at the time of patient enrollment.
  • Adult patients at the time of informed consent signature
  • Patients able to understand and willing to comply with protocol requirements, instructions, and restrictions
  • Residents of Canada

Exclusion Criteria4

  • Patients who have previously screened positive for PsA through PEST.
  • Patients who have been diagnosed with PsA.
  • Patients who have been diagnosed with inflammatory arthritis unrelated to PsA (rheumatoid arthritis, reactive arthritis, enteropathic arthritis, axial spondyloarthritis)
  • Patients treated with a bDMARD for moderate-to-severe plaque PsO or any other medical condition within the last 6 months prior to patient enrollment.

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Interventions

DIAGNOSTIC_TESTPEST Screening group

PEST Screening group


Locations(21)

Novartis Investigative Site

Calgary, Alberta, Canada

Novartis Investigative Site

Kelowna, British Columbia, Canada

Novartis Investigative Site

Surrey, British Columbia, Canada

Novartis Investigative Site

Winnipeg, Manitoba, Canada

Novartis Investigative Site

Fredericton, New Brunswick, Canada

Novartis Investigative Site

Hamilton, Ontario, Canada

Novartis Investigative Site

Hamilton, Ontario, Canada

Novartis Investigative Site

Hamilton, Ontario, Canada

Novartis Investigative Site

Markham, Ontario, Canada

Novartis Investigative Site

North York, Ontario, Canada

Novartis Investigative Site

Richmond Hill, Ontario, Canada

Novartis Investigative Site

Stoney Creek, Ontario, Canada

Novartis Investigative Site

Toronto, Ontario, Canada

Novartis Investigative Site

Waterloo, Ontario, Canada

Novartis Investigative Site

Montreal, Quebec, Canada

Novartis Investigative Site

Montreal, Quebec, Canada

Novartis Investigative Site

Québec, Quebec, Canada

Novartis Investigative Site

Ste-Foy, Quebec, Canada

Novartis Investigative Site

Verdun, Quebec, Canada

Novartis Investigative Site

Saskatoon, Saskatchewan, Canada

Novartis Investigative Site

Saskatoon, Saskatchewan, Canada

View Full Details on ClinicalTrials.gov

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NCT06382051


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