PVI Predictors in Laparoscopic Hysterectomy
Predictors of Pleth Variability Index During Laparoscopically Assisted Vaginal Hysterectomy
Wonkwang University Hospital
50 participants
Jul 1, 2026
OBSERVATIONAL
Conditions
Summary
This observational study investigates the predictors of Pleth Variability Index (PVI) changes in euvolemic patients undergoing laparoscopic-assisted vaginal hysterectomy (LAVH). The primary objective is to quantify changes in PVI (ΔPVI) across six intraoperative time points associated with positional shifts. Secondary objectives include identifying key predictors of significant PVI change (ΔPVI ≥ 5%), such as passive leg raising, Trendelenburg position, body mass index (BMI), and intraabdominal pressure. Additional variables including perfusion index, mean arterial pressure, bispectral index, skin temperature, age, and anesthetic agent will be evaluated as potential modulators. Findings aim to support individualized fluid management strategies in LAVH.
Eligibility
Inclusion Criteria1
- adult females aged 19-70 years (American Society of Anesthesiologists physical status I-III) scheduled for elective LAVH.
Exclusion Criteria1
- emergency surgery, severe cardiac or pulmonary disease, renal failure, pregnancy, or conditions contraindicating fluid administration. Participants were consecutively recruited during preoperative consultations.
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Interventions
"PVI is continuously monitored using the Masimo Radical-7 pulse oximetry device to evaluate respiratory variation in the plethysmographic waveform amplitude during laparoscopic-assisted vaginal hysterectomy (LAVH). No fluid intervention is applied; device use is for observational measurement of fluid responsiveness."
Locations(1)
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NCT06981221