Fluid responsiveness Clinical Trials

11 recruitingLast updated: May 21, 2026

There are 11 actively recruiting fluid responsiveness clinical trials across 8 countries. Studies span Not Applicable. Top locations include Vienna, Austria, Guangzhou, Guangdong, China, Istanbul, Istanbul, Turkey (Türkiye). Updated daily from ClinicalTrials.gov.


Fluid responsiveness Trials at a Glance

11 actively recruiting trials for fluid responsiveness are listed on ClinicalTrialsFinder across 6 cities in 8 countries. The largest study group is Not Applicable with 3 trials, with the heaviest enrollment activity in Vienna, Guangzhou, and Istanbul. Lead sponsors running fluid responsiveness studies include Medical University of Vienna, Bicetre Hospital, and Azienda Ospedaliero Universitaria Maggiore della Carita.

Browse fluid responsiveness trials by phase

About Fluid responsiveness Clinical Trials

Looking for clinical trials for Fluid responsiveness? There are currently 10 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Fluid responsiveness trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Fluid responsiveness clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 111 of 11 trials

Recruiting

Prediction of Fluid Responsiveness Using the Femoral Vein-to-Artery Diameter Ratio

Acute circulatory failureShockFluid responsiveness
Istanbul University - Cerrahpasa100 enrolled1 locationNCT07546656
Recruiting

Comparison of Acoustic Variability Index (AVI) and Pulse Pressure Variation (PPV) for Predicting Fluid Responsiveness in Mechanically Ventilated Patients

Hemodynamic MonitoringAnesthesia GeneralFluid Responsiveness Predictability
Signal House Co., Ltd.122 enrolled1 locationNCT07516470
Recruiting
Not Applicable

Fluid Management and Individualized Resuscitation in Sepsis

SepsisShockEmergency Medicine+3 more
University Medical Center Groningen188 enrolled1 locationNCT07009665
Recruiting

Evaluation of the Variation of the Sub-pulmonary Velocity-time Integral to Predict Fluid Responsiveness

fluid resuscitationFluid Responsiveness Predictability
Hospital Nord205 enrolled2 locationsNCT07202637
Recruiting
Not Applicable

Hemodynamic Monitoring and Fluid Responsiveness in Venoarterial Extracorporeal Membrane Oxygenation (VA ECMO) - "HemodynamECMOnitoring-VA Study"

PneumoniaARDSHemodynamic Monitoring+3 more
Medical University of Vienna30 enrolled1 locationNCT06593756
Recruiting
Not Applicable

Hemodynamic Monitoring and Fluid Responsiveness in Venovenous Extracorporeal Membrane Oxygenation (VV ECMO) - "HemodynamECMOnitoring-VV Study"

PneumoniaARDSHemodynamic Monitoring+3 more
Medical University of Vienna30 enrolled1 locationNCT06593717
Recruiting

Effectiveness of the Pressure Recording Analytical Method in Predicting Fluid Responsiveness in Pediatric Critical Care Patients

Fluid responsivenessHypovolemiaHemorrhage
Assistance Publique - Hôpitaux de Paris100 enrolled1 locationNCT04186416
Recruiting

Fluid Responsiveness and Venous Congestion Evolution During Volume Expansion

fluid challengeFluid responsivenessHemodynamic+1 more
Bicetre Hospital64 enrolled3 locationsNCT06772038
Recruiting

Passive Leg Raise and Mini-fluid Challenge Effect on Various Cardiac Output Surrogates for Fluid Responsiveness

Fluid responsiveness
CentraCare64 enrolled1 locationNCT06390423
Recruiting

Tidal Volume Challenge During Neurosurgery for Assessing Fluid Responsiveness. A Interventional Prospective Trial

Tidal Volume Challengestroke volume variation pulse pressure variationAnesthesia Neurosurgery+2 more
Azienda Ospedaliero Universitaria Maggiore della Carita50 enrolled1 locationACTRN12618000351213
Recruiting

Effects of patient's inspiratory effort, as assessed by esophageal pressure, on Pulse Pressure Variation assessment of fluid responsiveness in patients undergoing mechanical ventilation.

Hemodynamic statusFluid responsiveness
Federico Longhini, MD20 enrolled1 locationACTRN12616000529448