RecruitingPhase 1Phase 2NCT06981741

Safety and Efficacy of hUC-MSC for the Treatment of Cartilage Damage in the Knee Joint

Phase I/IIa Study to Test the Safety and Efficacy of MSC From Umbilical Cord Tissue (UC-MSC) for the Treatment of Cartilage Damage in the Knee Joint

Sponsor

BIONCaRT GmbH

Enrollment

55 participants

Start Date

Nov 10, 2025

Study Type

INTERVENTIONAL

Conditions

Cartilage Damage

Summary

Testing the safety and efficacy of MSC from umbilical cord tissue (UC-MSC) for the treatment of cartilage damage in the knee joint

Eligibility

Min Age: 18 YearsMax Age: 60 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a biological treatment called BP CC 001 for people with cartilage damage. The study is currently recruiting participants at 7 locations. People eligible for this study include aged 18 Years to 60 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BIOLOGICALBP CC 001

10-20 x 10\^6 UC-MSC in 1 ml suspension, applied to a collagen carrier structure (Chondro-Gide®)

Locations(7)

Klinikum Altenburger Land, Klinik für Orthopädie und Unfallchirurgie

Altenburg, Germany

St. Nikolaus Stifts-Hospital

Andernach, Germany

Sozialstiftung Bamberg Klinikum am Bruderwald, Klinik für Orthopädie und Unfallchirurgie

Bamberg, Germany

Evangelisches Waldkrankenhaus Spandau

Berlin, Germany

GFO Kliniken Niederrhein, St. Vinzenz Hospital Dinslaken

Dinslaken, Germany

UniversitätsCentrum für Orthopädie, Unfall- & Plastische Chirurgie, Universitätsklinikum Carl Gustav Carus an der TU Dresden

Dresden, Germany

Maria-Josef-Hospital Greven, Klinik für Unfallchirurgie und Orthopädie

Greven, Germany

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NCT06981741

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