RecruitingPhase 2NCT06983080

Efficacy of Trazodone to Treat Insomnia in Older Adults (TRADITION Study)

The Efficacy of Trazodone for the Treatment of Insomnia in Older Adults: A Randomized Controlled Trial (The TRADITION Study)

Sponsor

Centre hospitalier de l'Université de Montréal (CHUM)

Enrollment

40 participants

Start Date

Nov 10, 2025

Study Type

INTERVENTIONAL

Conditions

Older People Drug Therapy Insomnia Chronic

Summary

This study aims to evaluate how effective trazodone is in treating insomnia in adults aged 65 years and older. The main question it aims to answer is : \- Is trazodone more effective than a placebo in reducing the severity of insomnia symptoms in older adults? Participants will : * Take 25 to 50 mg of trazodone or a matching placebo before bed for 28 days. After a 2-week break, they will then take the other medication for another 28 days. * Visit the clinic three times for checkup and test * Complete a sleep diary and wear an actimeter during the night.

Eligibility

Min Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Trazodone 25 mg for people with drug therapy, insomnia chronic, and other related conditions. The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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