RecruitingNCT06984731

The Safety and Efficacy of Radiofrequency Ablation After Left Atrial Appendage Occlusion.

Clinical Trial Protocol for Safety and Efficacy of Transcatheter Ablation After Left Atrial Appendicular Occlusion With WATCHMAN FLX


Sponsor

Affiliated Hospital of Nantong University

Enrollment

210 participants

Start Date

Apr 21, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

Objective: To evaluate the safety and efficacy of transcatheter atrial fibrillation ablation 1 month after WATCHMAN FLX left atrial appendage closure in patients with nonvalvular atrial fibrillation.


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether a heart procedure that combines closing off a small pouch in the heart (called the left atrial appendage) with a procedure to correct an irregular heartbeat (ablation) is safe and effective for people with a type of abnormal heart rhythm called atrial fibrillation. **You may be eligible if...** - You are 18 or older - You have been diagnosed with non-valvular atrial fibrillation (irregular heartbeat not caused by a heart valve problem) - You are already a candidate for both the WATCHMAN FLX device implant and atrial fibrillation ablation - Your heart anatomy is suitable for the WATCHMAN FLX device **You may NOT be eligible if...** - Your atrial fibrillation is caused by a heart valve problem or other structural heart disease - You have a blood clot in your heart or a recent clotting event - You have a serious bleeding disorder or recent major bleeding - You are pregnant or breastfeeding - You have severe liver, kidney, or other serious illness - You are unlikely to complete follow-up visits Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREleft atrial appendage closure

Patients with atrial fibrillation underwent transcatheter radiofrequency cardiac ablation 1 month after left atrial appendage closure with WATCHMAN FLX

PROCEDUREradiofrequency ablation

Patients with atrial fibrillation underwent transcatheter radiofrequency cardiac ablation 1 month after left atrial appendage closure with WATCHMAN FLX


Locations(1)

Affiliated hospital of Nantong University

Nantong, Jiangsu, China

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NCT06984731


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