RecruitingNot ApplicableNCT06986590

Addressing Hypertension Care in Africa Program

Addressing Hypertension Care in Africa (ADHINCRA) Program


Sponsor

Johns Hopkins University

Enrollment

800 participants

Start Date

Jan 9, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The ADHINCRA Program is a bundle of multilevel evidence-based interventions that address multiple predictors of controlled hypertension, including patient-, provider-, and health system-level factors. The successful implementation of the ADHINCRA program will provide a rigorous and scalable model for improving hypertension control in Africa, which would ultimately reduce the risk of cardiovascular disease, stroke and kidney disease.


Eligibility

Min Age: 18 YearsMax Age: 70 Years

Inclusion Criteria6

  • Aged 18 -70 years.
  • Diagnosis of hypertension and elevated systolic blood pressure measure (≥140 mmHg) on the most recent clinic visit without a diabetes diagnosis.
  • Hypertension treatment naive or on monotherapy.
  • Receives primary care at one of the participating sites.
  • Willing and able to provide informed consent in English, Twi, Dagbani, Ewe, Hausa, or Yoruba.
  • Owns a smartphone (Android or iOS).

Exclusion Criteria8

  • Age \<18 years or \>70 years.
  • Severely elevated BP (≥180/110mmHg).
  • Diagnosis of stroke, coronary artery disease, or kidney disease.
  • Diagnosis of end-stage renal disease (ESRD) treated with dialysis.
  • Serious medical condition which either limits life expectancy or requires active management (e.g., cancer).
  • Cognitive impairment or other conditions preventing study participation
  • Pregnant or currently nursing a child
  • Unwilling to provide informed consent

Interventions

BEHAVIORALADHINCRA Program

The ADHINCRA Program is a nurse-led intervention that includes the use of home blood pressure monitoring, a mobile health app, lifestyle counselling, and a simplified hypertension treatment protocol to achieve blood pressure control among people diagnosed with hypertension.


Locations(17)

Johns Hopkins University

Baltimore, Maryland, United States

Dominase SDA Hospital

Bekwai, Ashanti Region, Ghana

Kumasi South Hospital

Kumasi, Ashanti Region, Ghana

Manhyia Government Hospital

Kumasi, Ashanti Region, Ghana

Tafo Government Hospital

Tafo, Ashanti Region, Ghana

Berekum Holy Family Hospital

Berekum, Bono, Ghana

St. John of God Catholic Hospital

Duayaw Nkwanta, Bono, Ghana

Northern Regional Hospital

Tamale, Northern Region, Ghana

Tamale Teaching Hospital

Tamale, Northern Region, Ghana

Ho Municipal Hospital

Ho, Volta Region, Ghana

South Tongu District Hospital

Sogakope, Volta Region, Ghana

Akure South Hospital

Akure, Ondo State, Nigeria

Akoko North East

Ondo, Ondo State, Nigeria

Akoko North West

Ondo, Ondo State, Nigeria

Akoko South East

Ondo, Ondo State, Nigeria

Akoko South West

Ondo, Ondo State, Nigeria

Owo General Hospital

Owo, Ondo State, Nigeria

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT06986590


Related Trials