RecruitingNot ApplicableNCT06966258

Inspire HER: Inspiring the Heart and Emotions for Radical Health

Sponsor

University of Alabama at Birmingham

Enrollment

90 participants

Start Date

Nov 15, 2025

Study Type

INTERVENTIONAL

Conditions

Obesity Cardiovascular Diseases Hypertension Diabetes Smoking Kidney Disease Hyperlipidemia Cardiovascular Kidney Metabolic Syndrome

Summary

Poor heart health puts Black women at risk for a shorter life with more illness than people of any other non-indigenous racial group. We will refine and conduct a randomized, wait-list controlled trial of Inspire HER (a heart health lifestyle intervention for Black women that provides health education, physical activity, and social resources). We will also compare Inspire HER and Black Impact (a heart health intervention for Black men) data to study how women and men respond differently to stress. This trial aligns with American Heart Association's pledge to address heart health equity through new interventions that consider the person and the circumstances with which they live.

Eligibility

Sex: FEMALEMin Age: 30 YearsMax Age: 79 Years

Plain Language Summary

Simplified for easier understanding

This study is testing a heart health program called Inspire HER designed specifically for Black women with elevated cardiovascular, kidney, and metabolic risk — aiming to reduce health disparities through community-based support and lifestyle interventions. **You may be eligible if...** - You identify as a Black woman - You are between 30 and 79 years old - You have been diagnosed with Stage 2 or higher cardiovascular-kidney-metabolic syndrome (a combination of heart, kidney, and metabolic health issues) - You speak English - You live in the metropolitan Birmingham, Alabama area **You may NOT be eligible if...** - Your healthcare provider has restricted you from physical activity Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALInspire HER Intervention

The Black Impact intervention is an academic-community-government partnership adapted from the Diabetes Prevention Program and American Heart Association Check, Change, Control programs based on stakeholder feedback and to afford incorporation of additional evidence-based strategies for influencing target outcomes. The intervention is a 24-week community-based lifestyle intervention to improve cardiovascular health among Black men. Each participant will be assigned to a group with \>5 participants based on participant proximity to a central community meeting location. Each team will be guided weekly by a health coach who delivers content and coaching around the lifestyle intervention modeled on the diabetes prevention program and check, change, control blood pressure program, a community health worker who helps to address social needs and connects participants to primary care services, and a trainer who leads physical activity. Teams meet for 90 minutes per week.