Comparing Super High-flux and High-flux Dialyzer Performance Among Hemodialysis Patient With Sepsis : a Randomized Control Trial

This study is comparing two types of dialysis filters — a "super high-flux" dialyzer and a standard "high-flux" dialyzer — in kidney failure patients who are critically ill with sepsis (a life-threatening response to infection), to see which filter better removes harmful inflammatory substances from the blood. **You may be eligible if...** - You have end-stage kidney disease (ESKD) requiring hemodialysis - You currently have sepsis with elevated interleukin-6 levels (IL-6 above 50 pg/mL, a marker of severe inflammation) **You may NOT be eligible if...** - You need continuous kidney replacement therapy (a different type of intensive dialysis) - You are pregnant or in another vulnerable category - You are expected to pass away within 24 hours - You have had an allergic reaction to the dialyzers used in this trial Talk to your doctor to see if this trial is right for you.