Effects of Nutritional Supplementation of Leucine and Polyunsaturated Fatty Acids on Muscle Health in the Elderly
Explore the Effects of Nutritional Supplementation of Leucine and Polyunsaturated Fatty Acids on Muscle Health in the Elderly
Chang Gung Memorial Hospital
90 participants
Jul 1, 2025
INTERVENTIONAL
Conditions
Summary
Population aging has become a significant global concern, and Taiwan is set to officially enter the "super-aged society" in 2025. As individuals age, various physiological functions gradually decline, including a reduction in muscle mass, which is a key aspect of the aging process. This interventional study aims to investigate the effects of leucine-rich protein combined with polyunsaturated fatty acid supplementation on middle-aged and elderly individuals (aged 50 and above) who are at high risk for sarcopenia.
Eligibility
Inclusion Criteria6
- Age ≥ 50 years
- ASMI < 7 kg/m2 in men
- ASMI < 5.7 kg/m2 in women
- Grip strength < 28 kg in men
- Grip strength < 18 kg in women
- Walk speed < 1 m/s
Exclusion Criteria6
- People who are allergic to supplements
- cancer
- heart failure
- kidney disease
- autoimmune disease
- neurodegenerative disease
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Interventions
Participants in animal-based oil group will follow a diet in which the primary fat source is animal-based oil. The diet will supplement for 12 weeks.
Participants in plant-based oil group will follow a diet in which the primary fat source is plant-based oil. The diet will supplement for 12 weeks.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06991855