Characterization of Placental Diffusion
Characterization of Placental Diffusion in Women With Diabetes Using DW-MRI
Hillel Yaffe Medical Center
40 participants
Jul 6, 2023
INTERVENTIONAL
Conditions
Summary
DW-MRI Allows a quantitative comparison of diffusion as an expression of tissue hypoxia. The investigators aim is to compare changes in placental diffusion in pregnant women with uncontrolled diabetes compared to healthy pregnant women using DW-MRI. The investigators hypothesize that placentas of diabetic mothers will show lower diffusion / perfusion compared to placentas of healthy women.
Eligibility
Inclusion Criteria2
- Women with PGAM (Pre-gestational diabetes) diagnosed before 20 weeks of pregnancy
- Women with GDMA (Gestational diabetes) diagnosed by OGTT after 20 weeks of pregnancy
Exclusion Criteria6
- pregnant women with placental hypoxia disease related in the past
- pregnant women with placental hypoxia disease related in the present
- non-singleton pregnancy
- women in active labor or rupture of membrane
- smoking women
- suspicion of placenta accreta
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Interventions
Predict changes in ovarian diffusion using DW-MRI scan
Locations(1)
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NCT06992245