Acute Exercise and Endogenous Glucose Production in Type 2 Diabetes: Implications for Glycemic Control and Treatment of Hepatic Steatosis

This study is looking at how a single bout of exercise affects blood sugar production from the liver in people with type 2 diabetes — and whether this response differs from healthy, lean individuals — to better understand how exercise works as a diabetes treatment. **You may be eligible if (type 2 diabetes group)...** - You are male or pre-menopausal female, aged 25–55 - You have type 2 diabetes with HbA1c of 7.5% or higher - You have excess liver fat (5.6% or above on MRI) - You are largely inactive (exercising 1 day or less per week) - Your weight has been stable for the past 3 months **You may NOT be eligible if...** - You are currently taking insulin, GLP-1 medications, or thiazolidinediones - You have serious heart, kidney, liver, or lung disease - You have resting blood pressure of 160/100 or higher - You have active cancer Talk to your doctor to see if this trial is right for you.