RecruitingNot ApplicableNCT06995638

Improving Executive Control in Cognitively Healthy Older Adults: the MUltitasking STrategy (MUST) Study

Web-based Technology and Cognitive Training: Improving Executive Control in Cognitively Healthy Older Adults: the MUltitasking STrategy (MUST) Study

Sponsor

Rutgers, The State University of New Jersey

Enrollment

130 participants

Start Date

Dec 10, 2025

Study Type

INTERVENTIONAL

Conditions

Alzheimer's Disease (AD)Healthy Aging

Summary

Developing efficient cognitive intervention for cognitively health older adults is a major public health goal, due to its potential for reducing age-related cognitive decline and Alzheimer's disease/dementia risk. Executive Control is a relevant cognitive target since it declines with aging and is critical for multi-tasking in daily life. The proposed research investigates whether playing a web-based cognitive complex game (the Breakfast Game) impacts cognitive performance in cognitively healthy older adults. To be enrolled in the study, participants will be asked to undergo a cognitive sassessment, health questionnires, and a blood exam. The intervention consist in one educational session on healthy aging, and 10 one-hour cognitive training sessions 2-3 times a week over one month. Participants will be asked to repeat the cognitive assessment within 1-2 weeks after the intervention, and after three months.

Eligibility

Min Age: 60 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This study is testing a multi-tasking strategy (MUST) brain training program to see whether it can improve executive function — the mental skills used for planning, focusing, and adapting — in healthy older adults aged 60 to 75. The training sessions are delivered online. **You may be eligible if...** - You are between 60 and 75 years old - You speak English well - You are willing and able to attend 2 in-person assessments, 1 blood test, and participate in online training sessions **You may NOT be eligible if...** - Your score on a standard memory/thinking test (MoCA) is below 26 - You have a known history of dementia, stroke, cognitive impairment, seizures, or other brain or psychiatric conditions - You take medications known to affect memory or thinking - You have sensory or physical impairments that prevent you from using a standard computer Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALWeb-based Cognitive Training (with strategy)

Participants will learn to play a complex online game using specific guidance or strategy.

BEHAVIORALWeb-based Cognitive Training (without strategy)

Participants will learn to play a complex online game without specific guidance or strategy.

Locations(1)

Rutgers New Jersey Medical School, Behavior Health Sciences Building, F-Level

Newark, New Jersey, United States

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NCT06995638

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