Partial Volume High-Dose Irradiation in Renal Cell Carcinoma for Intra-TUmoural Control ALongside Current Management

This study tests high-dose radiation therapy targeted at only part of a kidney cancer tumor — rather than the whole tumor — to see whether this can control tumor growth while preserving surrounding healthy tissue. It is intended for patients who cannot have surgery or other ablative treatments. **You may be eligible if...** - You have been diagnosed with renal cell carcinoma (kidney cancer), confirmed by biopsy or a clinical team review - Surgery, ablation, or other local treatments are not appropriate for your situation - You are 18 or older with a Karnofsky Performance Status of at least 50 (able to care for yourself) - Your blood counts and organ function are adequate **You may NOT be eligible if...** - Your expected survival is less than 6 months - You have uncontrolled brain metastases - You have already had so much radiation that more cannot safely be delivered - You have another active primary cancer - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.