RecruitingNot ApplicableNCT06999837

[68Ga]Ga-PSMA PET/CT in Hepatocellular Carcinoma: Impact of Multiparametric Dynamic Whole-body Imaging and Kinetic Modeling.


Sponsor

Nantes University Hospital

Enrollment

40 participants

Start Date

Sep 23, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to evaluate the use of multiparametric dynamic whole-body \[68Ga\]Ga-PSMA PET/CT imaging in newly diagnosed HCC patients or in HCC patients with recent suspicion of refractory, residual, or recurrent disease.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether a type of imaging scan called PSMA PET/CT — typically used for prostate cancer — can also be useful for detecting and monitoring liver cancer (hepatocellular carcinoma, or HCC). **You may be eligible if...** - You are 18 or older - You have been diagnosed with liver cancer (HCC) confirmed by biopsy or imaging, or you have known HCC and need imaging to check for recurrence - You are in reasonably good health (ECOG 0–2) and your liver function is at Child-Pugh A level - You are expected to live at least 6 months **You may NOT be eligible if...** - You have an allergy to the imaging agent (PSMA-11) - You need emergency surgery for a bleeding liver tumor - You have had radioembolization in the last 3 months - You have serious heart disease or recently had major surgery - You have another active cancer (other than certain treated skin or cervical cancers) - You are pregnant or unwilling to use contraception after the scan Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

RADIATION[68Ga]Ga-PSMA-11

Dynamic whole-body \[68Ga\]Ga-PSMA acquisition to HCC patients


Locations(2)

HU Paris Nord APHP

Clichy, France

CHU de Nantes

Nantes, France

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NCT06999837


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