Impact of Persistent Inflammation-Immunosuppression-Catabolism Syndrome (PICS) on the Respiratory Physiology in Patients With Prolonged Mechanical Ventilation
National Taiwan University Hospital
40 participants
Mar 18, 2025
OBSERVATIONAL
Conditions
Summary
Past research on PICS has mainly focused on the predictability and prognosis of PICS occurrence in ICU patients. Still, there is currently insufficient research on the role of PICS in the care setting of patients who have stabilized and are transferred to respiratory care units such as Respiratory Care Centers (RCCs) for weaning attempts. To understand the impact of PICS on the respiratory physiology of patients undergoing weaning from prolonged mechanical ventilation, investigators propose a one-year research plan
Eligibility
Inclusion Criteria4
- Patients are still receiving ventilator support when transferred to the ward where the study is conducted.
- Use the respirator continuously for at least 10 days.
- Vital signs are stable: blood pressure systolic blood pressure is not lower than 70 mmHg; heartbeat is not lower than 50/min and not higher than 160/min; respiratory rate is not higher than 50/min.
- When using respirator support, the oxygen concentration should not exceed 60%.
Exclusion Criteria1
- ．At least one of the following conditions occurs: 1. Pregnancy. 2. The patient refuses to undergo weaning from the respirator training. 3. The patient has no ability to drive spontaneous breathing.
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Locations(1)
View Full Details on ClinicalTrials.gov
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NCT07002710