RecruitingNCT07018037
Role of TTV During First-line Immunotherapy Treatment in Patients With Renal Cell Carcinoma
Pilot Study to Describe the Role of TTV During First-line Immunotherapy Treatment in Patients With Renal Cell Carcinoma
Sponsor
Regina Elena Cancer Institute
Enrollment
20 participants
Start Date
Jan 29, 2025
Study Type
OBSERVATIONAL
Conditions
Summary
The aim of this project is to descriptively explore the trend of torquetenovirus viral load TTV during therapy with immune checkpoint inhibitor ICI in these patients, to evaluate a possible role of this virus as a biomarker of response.
Eligibility
Min Age: 18 Years
Inclusion Criteria6
- Patients over 18 years of age;
- Histological diagnosis of clear cell renal cell carcinoma;
- Evidence of advanced or metastatic disease;
- Patients diagnosed with metastatic clear cell renal cell carcinoma about to start first-line immunotherapy (ICI + ICI or ICI + TKI);
- Patients able to comply with the study procedures.
- Patients who give written informed consent personally or through a witness (study participation and data processing), before any study-specific procedure is started.
Exclusion Criteria5
- Previous neoplasms;
- Previous antineoplastic treatments;
- Previous steroid treatments;
- Active viral infections (e.g., HCV, HIV, etc.);
- Lack of autonomy in adhering to study procedures.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07018037
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